| 1 | Fri 23 Aug | 73-2 v Borussia MönchengladbachBorussia Mönchengladbach 2-3 Bayer 04 Leverkusen | German Bundesliga |
| 2 | Sat 5 Oct | 72-2 v Holstein KielBayer 04 Leverkusen 2-2 Holstein Kiel | German Bundesliga |
| 3 | Wed 23 Oct | 71-1 v BrestBrest 1-1 Bayer 04 Leverkusen | UEFA Champions League Matchday 3 |
| 4 | Fri 1 Nov | 70-0 v VfB StuttgartBayer 04 Leverkusen 0-0 VfB Stuttgart | German Bundesliga |
| 5 | Tue 5 Nov | 70-4 v LiverpoolLiverpool 4-0 Bayer 04 Leverkusen | UEFA Champions League Matchday 4 |
| 6 | Sat 9 Nov | 71-1 v VfL BochumVfL Bochum 1-1 Bayer 04 Leverkusen | German Bundesliga |
| 7 | Sat 18 Jan | 73-1 v Borussia MönchengladbachBayer 04 Leverkusen 3-1 Borussia Mönchengladbach | German Bundesliga |
| 8 | Tue 21 Jan | 71-2 v Atlético MadridAtlético Madrid 2-1 Bayer 04 Leverkusen | UEFA Champions League Matchday 7 |
| 9 | Wed 29 Jan | 72-0 v Sparta PragueBayer 04 Leverkusen 2-0 Sparta Prague | UEFA Champions League Matchday 8 |
| 10 | Sat 1 Mar | 74-1 v Eintracht FrankfurtEintracht Frankfurt 1-4 Bayer 04 Leverkusen | German Bundesliga |
| 11 | Sat 5 Apr | 71-0 v 1 FC Heidenheim1 FC Heidenheim 0-1 Bayer 04 Leverkusen | German Bundesliga |
| 12 | Sat 12 Apr | 7 0-0 v 1 FC Union BerlinBayer 04 Leverkusen 0-0 1 FC Union Berlin | German Bundesliga |
| 13 | Sat 26 Apr | 72-0 v FC AugsburgBayer 04 Leverkusen 2-0 FC Augsburg | German Bundesliga |
| 14 | Sun 11 May | 72-4 v Borussia DortmundBayer 04 Leverkusen 2-4 Borussia Dortmund | German Bundesliga |
| 15 | Sat 17 May | 72-2 v Mainz 05Mainz 05 2-2 Bayer 04 Leverkusen | German Bundesliga |
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