| 1 | Sat 26 Aug | 22 3-0 v Borussia MönchengladbachBorussia Mönchengladbach 0-3 Bayer 04 Leverkusen | German Bundesliga | 2 |
| 2 | Sat 2 Sep | 225-1 v Darmstadt 98Bayer 04 Leverkusen 5-1 Darmstadt 98 | German Bundesliga | 2 |
| 3 | Thu 21 Sep | 224-0 v HäckenBayer 04 Leverkusen 4-0 Häcken | UEFA Europa League Group H | 1 |
| 4 | Sun 24 Sep | 224-1 v 1 FC HeidenheimBayer 04 Leverkusen 4-1 1 FC Heidenheim | German Bundesliga | 2 |
| 5 | Sun 8 Oct | 223-0 v 1 FC KölnBayer 04 Leverkusen 3-0 1 FC Köln | German Bundesliga | 1 |
| 6 | Thu 26 Oct | 225-1 v FK QarabağBayer 04 Leverkusen 5-1 FK Qarabağ | UEFA Europa League Group H | 1 |
| 7 | Thu 9 Nov | 221-0 v FK QarabağFK Qarabağ 0-1 Bayer 04 Leverkusen | UEFA Europa League Group H | 1 |
| 8 | Thu 30 Nov | 22 2-0 v HäckenHäcken 0-2 Bayer 04 Leverkusen | UEFA Europa League Group H | 1 |
| 9 | Sun 3 Dec | 221-1 v Borussia DortmundBayer 04 Leverkusen 1-1 Borussia Dortmund | German Bundesliga | 1 |
| 10 | Sun 17 Dec | 223-0 v Eintracht FrankfurtBayer 04 Leverkusen 3-0 Eintracht Frankfurt | German Bundesliga | 1 |
| 11 | Wed 20 Dec | 224-0 v VfL BochumBayer 04 Leverkusen 4-0 VfL Bochum | German Bundesliga | 1 |
| 12 | Thu 11 Apr | 222-0 v West Ham UnitedBayer 04 Leverkusen 2-0 West Ham United | UEFA Europa League Quarter Final | 1 |
| 13 | Sun 14 Apr | 225-0 v Werder BremenBayer 04 Leverkusen 5-0 Werder Bremen | German Bundesliga | 1 |
| 14 | Sun 5 May | 225-1 v Eintracht FrankfurtEintracht Frankfurt 1-5 Bayer 04 Leverkusen | German Bundesliga | 1 |
| 15 | Sun 12 May | 225-0 v VfL BochumVfL Bochum 0-5 Bayer 04 Leverkusen | German Bundesliga | 1 |
| 16 | Sat 18 May | 222-1 v FC AugsburgBayer 04 Leverkusen 2-1 FC Augsburg | German Bundesliga | 1 |
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