| 1 | Wed 13 Dec | 12-1 v Young BoysRB Leipzig 2-1 Young Boys | UEFA Champions League Group G |
| 2 | Sun 4 Feb | 12-0 v 1 FC Union BerlinRB Leipzig 2-0 1 FC Union Berlin | German Bundesliga |
| 3 | Sat 10 Feb | 12-2 v FC AugsburgFC Augsburg 2-2 RB Leipzig | German Bundesliga |
| 4 | Tue 13 Feb | 10-1 v Real MadridRB Leipzig 0-1 Real Madrid | UEFA Champions League Round of 16 |
| 5 | Sat 17 Feb | 12-0 v Borussia MönchengladbachRB Leipzig 2-0 Borussia Mönchengladbach | German Bundesliga |
| 6 | Sat 2 Mar | 14-1 v VfL BochumVfL Bochum 1-4 RB Leipzig | German Bundesliga |
| 7 | Wed 6 Mar | 11-1 v Real MadridReal Madrid 1-1 RB Leipzig | UEFA Champions League Round of 16 |
| 8 | Sat 9 Mar | 12-0 v Darmstadt 98RB Leipzig 2-0 Darmstadt 98 | German Bundesliga |
| 9 | Fri 15 Mar | 15-1 v 1 FC Köln1 FC Köln 1-5 RB Leipzig | German Bundesliga |
| 10 | Fri 22 Mar | 11-0 v TurkeyHungary 1-0 Turkey | International Friendly |
| 11 | Sat 30 Mar | 10-0 v Mainz 05RB Leipzig 0-0 Mainz 05 | German Bundesliga |
| 12 | Sat 6 Apr | 14-1 v SC FreiburgSC Freiburg 1-4 RB Leipzig | German Bundesliga |
| 13 | Sat 13 Apr | 13-0 v VfL WolfsburgRB Leipzig 3-0 VfL Wolfsburg | German Bundesliga |
| 14 | Sat 20 Apr | 12-1 v 1 FC Heidenheim1 FC Heidenheim 1-2 RB Leipzig | German Bundesliga |
| 15 | Sat 27 Apr | 14-1 v Borussia DortmundRB Leipzig 4-1 Borussia Dortmund | German Bundesliga |
| 16 | Fri 3 May | 11-1 v 1899 Hoffenheim1899 Hoffenheim 1-1 RB Leipzig | German Bundesliga |
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