| 1 | Sat 15 Aug 2020 | 260-1 v Sporting de CharleroiSporting de Charleroi 1-0 KV Oostende |
| 2 | Mon 24 Aug 2020 | 260-0 v Sint-Truidense VVSint-Truidense VV 0-0 KV Oostende |
| 3 | Fri 28 Aug 2020 | 262-2 v RSC AnderlechtKV Oostende 2-2 RSC Anderlecht |
| 4 | Sat 12 Sep 2020 | 26 1-0 v MechelenMechelen 0-1 KV Oostende |
| 5 | Sat 19 Sep 2020 | 263-1 v Oud-Heverlee LeuvenKV Oostende 3-1 Oud-Heverlee Leuven |
| 6 | Mon 28 Sep 2020 | 262-2 v KRC GenkKRC Genk 2-2 KV Oostende |
| 7 | Sun 4 Oct 2020 | 263-0 v Royal Excel MouscronKV Oostende 3-0 Royal Excel Mouscron |
| 8 | Sun 25 Oct 2020 | 263-0 v SV Zulte WaregemKV Oostende 3-0 SV Zulte Waregem |
| 9 | Sun 1 Nov 2020 | 26 0-1 v Standard LiègeStandard Liège 1-0 KV Oostende |
| 10 | Sun 8 Nov 2020 | 261-3 v Club BruggeKV Oostende 1-3 Club Brugge |
| 11 | Sat 21 Nov 2020 | 261-1 v Royal AntwerpKV Oostende 1-1 Royal Antwerp |
| 12 | Tue 24 Nov 2020 | 260-2 v Waasland-BeverenWaasland-Beveren 2-0 KV Oostende |
| 13 | Sun 29 Nov 2020 | 261-3 v KV KortrijkKV Kortrijk 3-1 KV Oostende |
| 14 | Sun 6 Dec 2020 | 262-1 v KAA GentKV Oostende 2-1 KAA Gent |
| 15 | Sat 12 Dec 2020 | 261-0 v Cercle BruggeCercle Brugge 0-1 KV Oostende |
| 16 | Sat 26 Dec 2020 | 262-1 v Oud-Heverlee LeuvenOud-Heverlee Leuven 1-2 KV Oostende |
| 17 | Sat 9 Jan 2021 | 263-2 v Sporting de CharleroiKV Oostende 3-2 Sporting de Charleroi |
| 18 | Tue 12 Jan 2021 | 261-1 v KAS EupenKV Oostende 1-1 KAS Eupen |
| 19 | Sat 16 Jan 2021 | 262-1 v KV KortrijkKV Oostende 2-1 KV Kortrijk |
| 20 | Sat 6 Feb 2021 | 263-1 v Sint-Truidense VVKV Oostende 3-1 Sint-Truidense VV |
| 21 | Wed 17 Feb 2021 | 263-1 v KRC GenkKV Oostende 3-1 KRC Genk |
| 22 | Sat 20 Feb 2021 | 261-1 v KAS EupenKAS Eupen 1-1 KV Oostende |
| 23 | Sat 27 Feb 2021 | 262-0 v MechelenKV Oostende 2-0 Mechelen |
| 24 | Mon 8 Mar 2021 | 260-1 v KAA GentKAA Gent 1-0 KV Oostende |
| 25 | Sat 3 Apr 2021 | 260-2 v Waasland-BeverenKV Oostende 0-2 Waasland-Beveren |
| 26 | Sun 11 Apr 2021 | 262-1 v Germinal BeerschotGerminal Beerschot 1-2 KV Oostende |
| 27 | Sun 18 Apr 2021 | 261-1 v Cercle BruggeKV Oostende 1-1 Cercle Brugge |
| 28 | Sat 1 May 2021 | 266-2 v Standard LiègeKV Oostende 6-2 Standard Liège |
| 29 | Sun 9 May 2021 | 263-5 v MechelenMechelen 5-3 KV Oostende |
| 30 | Thu 13 May 2021 | 261-2 v KAA GentKAA Gent 2-1 KV Oostende |
| 31 | Sun 16 May 2021 | 260-4 v KAA GentKV Oostende 0-4 KAA Gent |
| 32 | Wed 19 May 2021 | 26 2-2 v MechelenKV Oostende 2-2 Mechelen |
| 33 | Sat 22 May 2021 | 263-1 v Standard LiègeStandard Liège 1-3 KV Oostende |
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