| 1 | Sat 14 Aug 2021 | 11-2 v Brighton & Hove AlbionBurnley 1-2 Brighton & Hove Albion | Premier League |
| 2 | Sat 21 Aug 2021 | 10-2 v LiverpoolLiverpool 2-0 Burnley | Premier League |
| 3 | Sun 29 Aug 2021 | 11-1 v Leeds UnitedBurnley 1-1 Leeds United | Premier League |
| 4 | Mon 13 Sep 2021 | 11-3 v EvertonEverton 3-1 Burnley | Premier League |
| 5 | Sat 18 Sep 2021 | 10-1 v ArsenalBurnley 0-1 Arsenal | Premier League |
| 6 | Tue 21 Sep 2021 | 14-1 v RochdaleBurnley 4-1 Rochdale | Carabao Cup Third Round |
| 7 | Sat 25 Sep 2021 | 12-2 v Leicester CityLeicester City 2-2 Burnley | Premier League |
| 8 | Sat 2 Oct 2021 | 10-0 v Norwich CityBurnley 0-0 Norwich City | Premier League |
| 9 | Sat 16 Oct 2021 | 10-2 v Manchester CityManchester City 2-0 Burnley | Premier League |
| 10 | Sat 23 Oct 2021 | 12-2 v SouthamptonSouthampton 2-2 Burnley | Premier League |
| 11 | Wed 27 Oct 2021 | 10-1 v Tottenham HotspurBurnley 0-1 Tottenham Hotspur | Carabao Cup Round of 16 |
| 12 | Sat 30 Oct 2021 | 13-1 v BrentfordBurnley 3-1 Brentford | Premier League |
| 13 | Sat 6 Nov 2021 | 11-1 v ChelseaChelsea 1-1 Burnley | Premier League |
| 14 | Sat 20 Nov 2021 | 13-3 v Crystal PalaceBurnley 3-3 Crystal Palace | Premier League |
| 15 | Wed 1 Dec 2021 | 10-0 v Wolverhampton WanderersWolverhampton Wanderers 0-0 Burnley | Premier League |
| 16 | Sat 4 Dec 2021 | 10-1 v Newcastle UnitedNewcastle United 1-0 Burnley | Premier League |
| 17 | Sun 12 Dec 2021 | 10-0 v West Ham UnitedBurnley 0-0 West Ham United | Premier League |
| 18 | Sat 8 Jan 2022 | 11-2 v Huddersfield TownBurnley 1-2 Huddersfield Town | Emirates FA Cup Third Round |
| 19 | Sun 23 Jan 2022 | 10-0 v ArsenalArsenal 0-0 Burnley | Premier League |
| 20 | Sat 5 Feb 2022 | 10-0 v WatfordBurnley 0-0 Watford | Premier League |
| 21 | Tue 8 Feb 2022 | 11-1 v Manchester UnitedBurnley 1-1 Manchester United | Premier League |
| 22 | Sun 13 Feb 2022 | 10-1 v LiverpoolBurnley 0-1 Liverpool | Premier League |
| 23 | Sat 19 Feb 2022 | 13-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-3 Burnley | Premier League |
| 24 | Wed 23 Feb 2022 | 11-0 v Tottenham HotspurBurnley 1-0 Tottenham Hotspur | Premier League |
| 25 | Sat 26 Feb 2022 | 11-1 v Crystal PalaceCrystal Palace 1-1 Burnley | Premier League |
| 26 | Tue 1 Mar 2022 | 10-2 v Leicester CityBurnley 0-2 Leicester City | Premier League |
| 27 | Sat 5 Mar 2022 | 10-4 v ChelseaBurnley 0-4 Chelsea | Premier League |
| 28 | Sat 12 Mar 2022 | 10-2 v BrentfordBrentford 2-0 Burnley | Premier League |
| 29 | Sat 2 Apr 2022 | 10-2 v Manchester CityBurnley 0-2 Manchester City | Premier League |
| 30 | Wed 6 Apr 2022 | 13-2 v EvertonBurnley 3-2 Everton | Premier League |
| 31 | Sun 10 Apr 2022 | 10-2 v Norwich CityNorwich City 2-0 Burnley | Premier League |
| 32 | Sun 17 Apr 2022 | 11-1 v West Ham UnitedWest Ham United 1-1 Burnley | Premier League |
| 33 | Thu 21 Apr 2022 | 12-0 v SouthamptonBurnley 2-0 Southampton | Premier League |
| 34 | Sun 24 Apr 2022 | 11-0 v Wolverhampton WanderersBurnley 1-0 Wolverhampton Wanderers | Premier League |
| 35 | Sat 30 Apr 2022 | 12-1 v WatfordWatford 1-2 Burnley | Premier League |
| 36 | Sat 7 May 2022 | 11-3 v Aston VillaBurnley 1-3 Aston Villa | Premier League |
| 37 | Sun 15 May 2022 | 1 0-1 v Tottenham HotspurTottenham Hotspur 1-0 Burnley | Premier League |
| 38 | Thu 19 May 2022 | 11-1 v Aston VillaAston Villa 1-1 Burnley | Premier League |
| 39 | Sun 22 May 2022 | 11-2 v Newcastle UnitedBurnley 1-2 Newcastle United | Premier League |
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