| 1 | Sat 6 Feb 2021 | 62-0 v BarrowBarrow 0-2 Cambridge United | Sky Bet League Two |
| 2 | Tue 9 Feb 2021 | 61-4 v Salford CitySalford City 4-1 Cambridge United | Sky Bet League Two |
| 3 | Sat 13 Feb 2021 | 60-0 v Southend UnitedCambridge United 0-0 Southend United | Sky Bet League Two |
| 4 | Sat 20 Feb 2021 | 63-0 v Mansfield TownMansfield Town 0-3 Cambridge United | Sky Bet League Two |
| 5 | Sat 27 Feb 2021 | 61-0 v Port ValePort Vale 0-1 Cambridge United | Sky Bet League Two |
| 6 | Tue 2 Mar 2021 | 60-1 v Scunthorpe UnitedCambridge United 0-1 Scunthorpe United | Sky Bet League Two |
| 7 | Sat 6 Mar 2021 | 61-0 v WalsallCambridge United 1-0 Walsall | Sky Bet League Two |
| 8 | Tue 9 Mar 2021 | 6 1-2 v Bolton WanderersBolton Wanderers 2-1 Cambridge United | Sky Bet League Two |
| 9 | Sat 13 Mar 2021 | 6 4-2 v Oldham AthleticOldham Athletic 2-4 Cambridge United | Sky Bet League Two |
| 10 | Sat 17 Apr 2021 | 61-0 v Newport CountyNewport County 0-1 Cambridge United | Sky Bet League Two |
| 11 | Tue 20 Apr 2021 | 64-2 v Leyton OrientLeyton Orient 2-4 Cambridge United | Sky Bet League Two |
| 12 | Sat 24 Apr 2021 | 60-1 v StevenageCambridge United 0-1 Stevenage | Sky Bet League Two |
| 13 | Fri 30 Apr 2021 | 64-5 v Harrogate TownHarrogate Town 5-4 Cambridge United | Sky Bet League Two |
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