| 1 | Sat 10 Aug | 16 0-2 v Stockport CountyStockport County 2-0 Cambridge United | Sky Bet League One |
| 2 | Tue 13 Aug | 161-2 v Queens Park RangersCambridge United 1-2 Queens Park Rangers | Carabao Cup First Round |
| 3 | Sat 17 Aug | 160-1 v Crawley TownCambridge United 0-1 Crawley Town | Sky Bet League One |
| 4 | Sat 24 Aug | 164-4 v BlackpoolCambridge United 4-4 Blackpool | Sky Bet League One |
| 5 | Sat 31 Aug | 160-2 v Bristol RoversBristol Rovers 2-0 Cambridge United | Sky Bet League One |
| 6 | Tue 3 Sep | 163-3 v BromleyBromley 3-3 Cambridge United | EFL Trophy Southern Group C |
| 7 | Sat 14 Sep | 16 1-2 v Mansfield TownMansfield Town 2-1 Cambridge United | Sky Bet League One |
| 8 | Tue 17 Sep | 161-2 v Charlton AthleticCambridge United 1-2 Charlton Athletic | EFL Trophy Southern Group C |
| 9 | Sat 21 Sep | 16 1-2 v Wycombe WanderersWycombe Wanderers 2-1 Cambridge United | Sky Bet League One |
| 10 | Sat 9 Nov | 161-6 v Peterborough UnitedPeterborough United 6-1 Cambridge United | Sky Bet League One |
| 11 | Tue 26 Nov | 161-1 v Bolton WanderersCambridge United 1-1 Bolton Wanderers | Sky Bet League One |
| 12 | Sat 30 Nov | 161-2 v Wigan AthleticCambridge United 1-2 Wigan Athletic | Emirates FA Cup Second Round |
| 13 | Tue 3 Dec | 160-3 v ReadingReading 3-0 Cambridge United | Sky Bet League One |
| 14 | Sat 7 Dec | 164-1 v Shrewsbury TownCambridge United 4-1 Shrewsbury Town | Sky Bet League One |
| 15 | Tue 10 Dec | 16 1-2 v Cheltenham TownCheltenham Town 2-1 Cambridge United | EFL Trophy Second Round |
| 16 | Sat 14 Dec | 162-2 v WrexhamWrexham 2-2 Cambridge United | Sky Bet League One |
| 17 | Thu 26 Dec | 161-2 v Charlton AthleticCharlton Athletic 2-1 Cambridge United | Sky Bet League One |
| 18 | Sat 4 Jan | 160-1 v Bristol RoversCambridge United 0-1 Bristol Rovers | Sky Bet League One |
| 19 | Sat 18 Jan | 162-2 v Bolton WanderersBolton Wanderers 2-2 Cambridge United | Sky Bet League One |
| 20 | Sat 25 Jan | 163-2 v Mansfield TownCambridge United 3-2 Mansfield Town | Sky Bet League One |
Football Web Pages