| 1 | Tue 6 Aug | 321-1 v Steaua BucharestSparta Prague 1-1 Steaua Bucharest |
| 2 | Tue 13 Aug | 323-2 v Steaua BucharestSteaua Bucharest 2-3 Sparta Prague |
| 3 | Wed 21 Aug | 322-0 v Malmö FFMalmö FF 0-2 Sparta Prague |
| 4 | Tue 27 Aug | 322-0 v Malmö FFSparta Prague 2-0 Malmö FF |
| 5 | Wed 18 Sep | 323-0 v SV Red Bull SalzburgSparta Prague 3-0 SV Red Bull Salzburg |
| 6 | Tue 1 Oct | 321-1 v VfB StuttgartVfB Stuttgart 1-1 Sparta Prague |
| 7 | Wed 23 Oct | 320-5 v Manchester CityManchester City 5-0 Sparta Prague |
| 8 | Wed 6 Nov | 32 1-2 v BrestSparta Prague 1-2 Brest |
| 9 | Tue 26 Nov | 320-6 v Atlético MadridSparta Prague 0-6 Atlético Madrid |
| 10 | Wed 11 Dec | 322-4 v FeyenoordFeyenoord 4-2 Sparta Prague |
| 11 | Wed 22 Jan | 320-1 v Inter MilanSparta Prague 0-1 Inter Milan |
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