| 1 | Sat 26 Aug | 280-2 v MonzaMonza 2-0 Empoli |
| 2 | Sun 3 Sep | 280-2 v JuventusEmpoli 0-2 Juventus |
| 3 | Sun 17 Sep | 280-7 v RomaRoma 7-0 Empoli |
| 4 | Sun 24 Sep | 280-1 v Inter MilanEmpoli 0-1 Inter Milan |
| 5 | Wed 27 Sep | 281-0 v SalernitanaEmpoli 1-0 Salernitana |
| 6 | Sun 1 Oct | 280-3 v BolognaBologna 3-0 Empoli |
| 7 | Fri 6 Oct | 280-0 v UdineseEmpoli 0-0 Udinese |
| 8 | Mon 23 Oct | 282-0 v FiorentinaFiorentina 0-2 Empoli |
| 9 | Mon 30 Oct | 280-3 v AtalantaEmpoli 0-3 Atalanta |
| 10 | Mon 6 Nov | 281-2 v FrosinoneFrosinone 2-1 Empoli |
| 11 | Sun 12 Nov | 281-0 v NapoliNapoli 0-1 Empoli |
| 12 | Sun 26 Nov | 283-4 v SassuoloEmpoli 3-4 Sassuolo |
| 13 | Sat 2 Dec | 281-1 v GenoaGenoa 1-1 Empoli |
| 14 | Mon 11 Dec | 281-1 v LecceEmpoli 1-1 Lecce |
| 15 | Sat 16 Dec | 280-1 v TorinoTorino 1-0 Empoli |
| 16 | Fri 22 Dec | 280-2 v LazioEmpoli 0-2 Lazio |
| 17 | Sat 30 Dec | 280-0 v CagliariCagliari 0-0 Empoli |
| 18 | Sun 7 Jan | 280-3 v AC MilanEmpoli 0-3 AC Milan |
| 19 | Sat 13 Jan | 28 1-2 v Hellas VeronaHellas Verona 2-1 Empoli |
| 20 | Sun 21 Jan | 283-0 v MonzaEmpoli 3-0 Monza |
| 21 | Sat 27 Jan | 281-1 v JuventusJuventus 1-1 Empoli |
| 22 | Sat 3 Feb | 28 0-0 v GenoaEmpoli 0-0 Genoa |
| 23 | Fri 9 Feb | 283-1 v SalernitanaSalernitana 1-3 Empoli |
| 24 | Sun 18 Feb | 281-1 v FiorentinaEmpoli 1-1 Fiorentina |
| 25 | Sat 24 Feb | 283-2 v SassuoloSassuolo 2-3 Empoli |
| 26 | Sun 3 Mar | 280-1 v CagliariEmpoli 0-1 Cagliari |
| 27 | Sun 10 Mar | 280-1 v AC MilanAC Milan 1-0 Empoli |
| 28 | Fri 15 Mar | 280-1 v BolognaEmpoli 0-1 Bologna |
| 29 | Mon 1 Apr | 28 0-2 v Inter MilanInter Milan 2-0 Empoli |
| 30 | Sat 6 Apr | 283-2 v TorinoEmpoli 3-2 Torino |
| 31 | Sat 13 Apr | 280-1 v LecceLecce 1-0 Empoli |
| 32 | Sat 20 Apr | 281-0 v NapoliEmpoli 1-0 Napoli |
| 33 | Sun 28 Apr | 280-2 v AtalantaAtalanta 2-0 Empoli |
| 34 | Sun 5 May | 280-0 v FrosinoneEmpoli 0-0 Frosinone |
| 35 | Sun 12 May | 280-2 v LazioLazio 2-0 Empoli |
| 36 | Sun 19 May | 281-1 v UdineseUdinese 1-1 Empoli |
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