| 1 | Sat 4 Aug 2018 | 202-3 v Wigan AthleticWigan Athletic 3-2 Sheffield Wednesday |
| 2 | Sat 11 Aug 2018 | 201-1 v Hull CitySheffield Wednesday 1-1 Hull City |
| 3 | Sun 19 Aug 2018 | 200-2 v BrentfordBrentford 2-0 Sheffield Wednesday |
| 4 | Wed 22 Aug 2018 | 20 2-1 v MillwallSheffield Wednesday 2-1 Millwall |
| 5 | Sat 25 Aug 2018 | 202-1 v Ipswich TownSheffield Wednesday 2-1 Ipswich Town |
| 6 | Sat 1 Sep 2018 | 202-1 v ReadingReading 1-2 Sheffield Wednesday |
| 7 | Sat 15 Sep 2018 | 202-2 v Stoke CitySheffield Wednesday 2-2 Stoke City |
| 8 | Wed 19 Sep 2018 | 201-2 v Nottingham ForestNottingham Forest 2-1 Sheffield Wednesday |
| 9 | Sat 22 Sep 2018 | 202-1 v Aston VillaAston Villa 1-2 Sheffield Wednesday |
| 10 | Fri 28 Sep 2018 | 201-1 v Leeds UnitedSheffield Wednesday 1-1 Leeds United |
| 11 | Wed 3 Oct 2018 | 202-2 v West Bromwich AlbionSheffield Wednesday 2-2 West Bromwich Albion |
| 12 | Sun 7 Oct 2018 | 202-1 v Bristol CityBristol City 1-2 Sheffield Wednesday |
| 13 | Fri 19 Oct 2018 | 201-2 v MiddlesbroughSheffield Wednesday 1-2 Middlesbrough |
| 14 | Tue 23 Oct 2018 | 200-3 v Queens Park RangersQueens Park Rangers 3-0 Sheffield Wednesday |
| 15 | Sat 27 Oct 2018 | 201-3 v Birmingham CityBirmingham City 3-1 Sheffield Wednesday |
| 16 | Sat 3 Nov 2018 | 200-4 v Norwich CitySheffield Wednesday 0-4 Norwich City |
| 17 | Fri 9 Nov 2018 | 200-0 v Sheffield UnitedSheffield United 0-0 Sheffield Wednesday |
| 18 | Sat 24 Nov 2018 | 201-2 v Derby CountySheffield Wednesday 1-2 Derby County |
| 19 | Tue 27 Nov 2018 | 201-0 v Bolton WanderersSheffield Wednesday 1-0 Bolton Wanderers |
| 20 | Sat 1 Dec 2018 | 202-4 v Blackburn RoversBlackburn Rovers 4-2 Sheffield Wednesday |
| 21 | Sat 8 Dec 2018 | 202-2 v Rotherham UnitedSheffield Wednesday 2-2 Rotherham United |
| 22 | Sat 15 Dec 2018 | 201-2 v Swansea CitySwansea City 2-1 Sheffield Wednesday |
| 23 | Sat 22 Dec 2018 | 201-0 v Preston North EndSheffield Wednesday 1-0 Preston North End |
| 24 | Wed 26 Dec 2018 | 201-0 v MiddlesbroughMiddlesbrough 0-1 Sheffield Wednesday |
| 25 | Sat 29 Dec 2018 | 201-1 v West Bromwich AlbionWest Bromwich Albion 1-1 Sheffield Wednesday |
| 26 | Tue 1 Jan 2019 | 201-1 v Birmingham CitySheffield Wednesday 1-1 Birmingham City |
| 27 | Sat 12 Jan 2019 | 200-3 v Hull CityHull City 3-0 Sheffield Wednesday |
| 28 | Sat 19 Jan 2019 | 201-0 v Wigan AthleticSheffield Wednesday 1-0 Wigan Athletic |
| 29 | Sat 2 Feb 2019 | 201-0 v Ipswich TownIpswich Town 0-1 Sheffield Wednesday |
| 30 | Sat 9 Feb 2019 | 200-0 v ReadingSheffield Wednesday 0-0 Reading |
| 31 | Tue 12 Feb 2019 | 200-0 v MillwallMillwall 0-0 Sheffield Wednesday |
| 32 | Sat 16 Feb 2019 | 202-2 v Rotherham UnitedRotherham United 2-2 Sheffield Wednesday |
| 33 | Sat 23 Feb 2019 | 203-1 v Swansea CitySheffield Wednesday 3-1 Swansea City |
| 34 | Tue 26 Feb 2019 | 202-0 v BrentfordSheffield Wednesday 2-0 Brentford |
| 35 | Mon 4 Mar 2019 | 200-0 v Sheffield UnitedSheffield Wednesday 0-0 Sheffield United |
| 36 | Sat 9 Mar 2019 | 20 1-1 v Derby CountyDerby County 1-1 Sheffield Wednesday |
| 37 | Tue 12 Mar 2019 | 202-0 v Bolton WanderersBolton Wanderers 0-2 Sheffield Wednesday |
| 38 | Sat 16 Mar 2019 | 204-2 v Blackburn RoversSheffield Wednesday 4-2 Blackburn Rovers |
| 39 | Sat 30 Mar 2019 | 200-0 v Stoke CityStoke City 0-0 Sheffield Wednesday |
| 40 | Sat 6 Apr 2019 | 201-3 v Aston VillaSheffield Wednesday 1-3 Aston Villa |
| 41 | Tue 9 Apr 2019 | 203-0 v Nottingham ForestSheffield Wednesday 3-0 Nottingham Forest |
| 42 | Sat 13 Apr 2019 | 200-1 v Leeds UnitedLeeds United 1-0 Sheffield Wednesday |
| 43 | Mon 22 Apr 2019 | 202-0 v Bristol CitySheffield Wednesday 2-0 Bristol City |
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