| 1 | Mon 6 Aug 2018 | 11-3 v Aston VillaHull City 1-3 Aston Villa |
| 2 | Sat 11 Aug 2018 | 11-1 v Sheffield WednesdaySheffield Wednesday 1-1 Hull City |
| 3 | Sat 18 Aug 2018 | 10-1 v Blackburn RoversHull City 0-1 Blackburn Rovers |
| 4 | Tue 21 Aug 2018 | 13-2 v Rotherham UnitedRotherham United 2-3 Hull City |
| 5 | Sat 25 Aug 2018 | 10-2 v Stoke CityStoke City 2-0 Hull City |
| 6 | Sat 1 Sep 2018 | 11-2 v Derby CountyHull City 1-2 Derby County |
| 7 | Sat 15 Sep 2018 | 12-0 v Ipswich TownHull City 2-0 Ipswich Town |
| 8 | Tue 18 Sep 2018 | 11-2 v Wigan AthleticWigan Athletic 2-1 Hull City |
| 9 | Sat 22 Sep 2018 | 10-3 v ReadingReading 3-0 Hull City |
| 10 | Sat 29 Sep 2018 | 11-1 v MiddlesbroughHull City 1-1 Middlesbrough |
| 11 | Tue 2 Oct 2018 | 10-1 v Leeds UnitedHull City 0-1 Leeds United |
| 12 | Sat 6 Oct 2018 | 10-1 v Sheffield UnitedSheffield United 1-0 Hull City |
| 13 | Sat 20 Oct 2018 | 11-1 v Preston North EndHull City 1-1 Preston North End |
| 14 | Wed 24 Oct 2018 | 10-1 v Bristol CityBristol City 1-0 Hull City |
| 15 | Sat 27 Oct 2018 | 11-0 v Bolton WanderersBolton Wanderers 0-1 Hull City |
| 16 | Sat 3 Nov 2018 | 11-0 v West Bromwich AlbionHull City 1-0 West Bromwich Albion |
| 17 | Sat 10 Nov 2018 | 13-3 v Birmingham CityBirmingham City 3-3 Hull City |
| 18 | Sat 24 Nov 2018 | 10-2 v Nottingham ForestHull City 0-2 Nottingham Forest |
| 19 | Tue 27 Nov 2018 | 10-0 v Norwich CityHull City 0-0 Norwich City |
| 20 | Sat 1 Dec 2018 | 13-2 v Queens Park RangersQueens Park Rangers 2-3 Hull City |
| 21 | Sat 8 Dec 2018 | 12-2 v MillwallMillwall 2-2 Hull City |
| 22 | Sat 15 Dec 2018 | 12-0 v BrentfordHull City 2-0 Brentford |
| 23 | Sat 22 Dec 2018 | 13-2 v Swansea CityHull City 3-2 Swansea City |
| 24 | Wed 26 Dec 2018 | 12-1 v Preston North EndPreston North End 1-2 Hull City |
| 25 | Sat 29 Dec 2018 | 12-0 v Leeds UnitedLeeds United 0-2 Hull City |
| 26 | Tue 1 Jan 2019 | 16-0 v Bolton WanderersHull City 6-0 Bolton Wanderers |
| 27 | Sat 12 Jan 2019 | 13-0 v Sheffield WednesdayHull City 3-0 Sheffield Wednesday |
| 28 | Sat 19 Jan 2019 | 12-2 v Aston VillaAston Villa 2-2 Hull City |
| 29 | Sat 26 Jan 2019 | 10-3 v Blackburn RoversBlackburn Rovers 3-0 Hull City |
| 30 | Sat 2 Feb 2019 | 12-0 v Stoke CityHull City 2-0 Stoke City |
| 31 | Sat 9 Feb 2019 | 10-2 v Derby CountyDerby County 2-0 Hull City |
| 32 | Tue 12 Feb 2019 | 12-2 v Rotherham UnitedHull City 2-2 Rotherham United |
| 33 | Sat 23 Feb 2019 | 11-5 v BrentfordBrentford 5-1 Hull City |
| 34 | Tue 26 Feb 2019 | 1 2-1 v MillwallHull City 2-1 Millwall |
| 35 | Sat 2 Mar 2019 | 12-0 v Birmingham CityHull City 2-0 Birmingham City |
| 36 | Sat 9 Mar 2019 | 10-3 v Nottingham ForestNottingham Forest 3-0 Hull City |
| 37 | Wed 13 Mar 2019 | 12-3 v Norwich CityNorwich City 3-2 Hull City |
| 38 | Sat 16 Mar 2019 | 12-2 v Queens Park RangersHull City 2-2 Queens Park Rangers |
| 39 | Sat 30 Mar 2019 | 1 2-0 v Ipswich TownIpswich Town 0-2 Hull City |
| 40 | Sat 6 Apr 2019 | 13-1 v ReadingHull City 3-1 Reading |
| 41 | Wed 10 Apr 2019 | 12-1 v Wigan AthleticHull City 2-1 Wigan Athletic |
| 42 | Sat 13 Apr 2019 | 10-1 v MiddlesbroughMiddlesbrough 1-0 Hull City |
| 43 | Fri 19 Apr 2019 | 12-3 v West Bromwich AlbionWest Bromwich Albion 3-2 Hull City |
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