| 1 | Sun 5 Aug 2018 | 31-3 v Leeds UnitedLeeds United 3-1 Stoke City |
| 2 | Sat 11 Aug 2018 | 31-1 v BrentfordStoke City 1-1 Brentford |
| 3 | Sat 18 Aug 2018 | 32-2 v Preston North EndPreston North End 2-2 Stoke City |
| 4 | Wed 22 Aug 2018 | 30-3 v Wigan AthleticStoke City 0-3 Wigan Athletic |
| 5 | Sat 25 Aug 2018 | 32-0 v Hull CityStoke City 2-0 Hull City |
| 6 | Sat 1 Sep 2018 | 3 1-2 v West Bromwich AlbionWest Bromwich Albion 2-1 Stoke City |
| 7 | Sat 15 Sep 2018 | 32-2 v Sheffield WednesdaySheffield Wednesday 2-2 Stoke City |
| 8 | Tue 18 Sep 2018 | 3 1-0 v Swansea CityStoke City 1-0 Swansea City |
| 9 | Sat 22 Sep 2018 | 32-3 v Blackburn RoversStoke City 2-3 Blackburn Rovers |
| 10 | Sat 29 Sep 2018 | 32-2 v Rotherham UnitedRotherham United 2-2 Stoke City |
| 11 | Tue 2 Oct 2018 | 32-0 v Bolton WanderersStoke City 2-0 Bolton Wanderers |
| 12 | Sat 6 Oct 2018 | 31-0 v Norwich CityNorwich City 0-1 Stoke City |
| 13 | Sat 20 Oct 2018 | 30-1 v Birmingham CityStoke City 0-1 Birmingham City |
| 14 | Tue 23 Oct 2018 | 31-1 v Sheffield UnitedSheffield United 1-1 Stoke City |
| 15 | Sat 27 Oct 2018 | 31-0 v Bristol CityBristol City 0-1 Stoke City |
| 16 | Wed 28 Nov 2018 | 32-1 v Derby CountyStoke City 2-1 Derby County |
| 17 | Sat 1 Dec 2018 | 32-2 v ReadingReading 2-2 Stoke City |
| 18 | Sat 8 Dec 2018 | 32-0 v Ipswich TownStoke City 2-0 Ipswich Town |
| 19 | Sat 15 Dec 2018 | 3 2-2 v Aston VillaAston Villa 2-2 Stoke City |
| 20 | Sat 22 Dec 2018 | 31-0 v MillwallStoke City 1-0 Millwall |
| 21 | Sat 12 Jan 2019 | 31-3 v BrentfordBrentford 3-1 Stoke City |
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