| 1 | Sat 4 Aug 2018 | 452-3 v Wigan AthleticWigan Athletic 3-2 Sheffield Wednesday |
| 2 | Sat 11 Aug 2018 | 451-1 v Hull CitySheffield Wednesday 1-1 Hull City |
| 3 | Sun 19 Aug 2018 | 450-2 v BrentfordBrentford 2-0 Sheffield Wednesday |
| 4 | Wed 22 Aug 2018 | 45 2-1 v MillwallSheffield Wednesday 2-1 Millwall |
| 5 | Sat 25 Aug 2018 | 452-1 v Ipswich TownSheffield Wednesday 2-1 Ipswich Town |
| 6 | Sat 1 Sep 2018 | 452-1 v ReadingReading 1-2 Sheffield Wednesday |
| 7 | Fri 28 Sep 2018 | 451-1 v Leeds UnitedSheffield Wednesday 1-1 Leeds United |
| 8 | Wed 3 Oct 2018 | 452-2 v West Bromwich AlbionSheffield Wednesday 2-2 West Bromwich Albion |
| 9 | Sun 7 Oct 2018 | 45 2-1 v Bristol CityBristol City 1-2 Sheffield Wednesday |
| 10 | Sat 24 Nov 2018 | 451-2 v Derby CountySheffield Wednesday 1-2 Derby County |
| 11 | Tue 27 Nov 2018 | 451-0 v Bolton WanderersSheffield Wednesday 1-0 Bolton Wanderers |
| 12 | Sat 1 Dec 2018 | 452-4 v Blackburn RoversBlackburn Rovers 4-2 Sheffield Wednesday |
| 13 | Sat 2 Feb 2019 | 451-0 v Ipswich TownIpswich Town 0-1 Sheffield Wednesday |
| 14 | Sat 9 Feb 2019 | 450-0 v ReadingSheffield Wednesday 0-0 Reading |
| 15 | Tue 12 Feb 2019 | 450-0 v MillwallMillwall 0-0 Sheffield Wednesday |
| 16 | Sat 16 Feb 2019 | 45 2-2 v Rotherham UnitedRotherham United 2-2 Sheffield Wednesday |
| 17 | Sat 23 Feb 2019 | 453-1 v Swansea CitySheffield Wednesday 3-1 Swansea City |
| 18 | Tue 26 Feb 2019 | 452-0 v BrentfordSheffield Wednesday 2-0 Brentford |
| 19 | Mon 4 Mar 2019 | 450-0 v Sheffield UnitedSheffield Wednesday 0-0 Sheffield United |
| 20 | Sat 30 Mar 2019 | 450-0 v Stoke CityStoke City 0-0 Sheffield Wednesday |
| 21 | Sat 6 Apr 2019 | 451-3 v Aston VillaSheffield Wednesday 1-3 Aston Villa |
| 22 | Sat 13 Apr 2019 | 450-1 v Leeds UnitedLeeds United 1-0 Sheffield Wednesday |
| 23 | Fri 19 Apr 2019 | 452-2 v Norwich CityNorwich City 2-2 Sheffield Wednesday |
| 24 | Mon 22 Apr 2019 | 452-0 v Bristol CitySheffield Wednesday 2-0 Bristol City |
| 25 | Sat 27 Apr 2019 | 453-3 v Preston North EndPreston North End 3-3 Sheffield Wednesday |
| 26 | Sun 5 May 2019 | 451-2 v Queens Park RangersSheffield Wednesday 1-2 Queens Park Rangers |
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