| 1 | Sun 5 Aug 2018 | 11-3 v Leeds UnitedLeeds United 3-1 Stoke City |
| 2 | Sat 11 Aug 2018 | 11-1 v BrentfordStoke City 1-1 Brentford |
| 3 | Sat 18 Aug 2018 | 12-2 v Preston North EndPreston North End 2-2 Stoke City |
| 4 | Wed 22 Aug 2018 | 10-3 v Wigan AthleticStoke City 0-3 Wigan Athletic |
| 5 | Sat 25 Aug 2018 | 12-0 v Hull CityStoke City 2-0 Hull City |
| 6 | Sat 1 Sep 2018 | 11-2 v West Bromwich AlbionWest Bromwich Albion 2-1 Stoke City |
| 7 | Sat 15 Sep 2018 | 12-2 v Sheffield WednesdaySheffield Wednesday 2-2 Stoke City |
| 8 | Tue 18 Sep 2018 | 11-0 v Swansea CityStoke City 1-0 Swansea City |
| 9 | Sat 22 Sep 2018 | 12-3 v Blackburn RoversStoke City 2-3 Blackburn Rovers |
| 10 | Sat 29 Sep 2018 | 12-2 v Rotherham UnitedRotherham United 2-2 Stoke City |
| 11 | Tue 2 Oct 2018 | 12-0 v Bolton WanderersStoke City 2-0 Bolton Wanderers |
| 12 | Sat 6 Oct 2018 | 11-0 v Norwich CityNorwich City 0-1 Stoke City |
| 13 | Sat 20 Oct 2018 | 10-1 v Birmingham CityStoke City 0-1 Birmingham City |
| 14 | Tue 23 Oct 2018 | 11-1 v Sheffield UnitedSheffield United 1-1 Stoke City |
| 15 | Sat 27 Oct 2018 | 11-0 v Bristol CityBristol City 0-1 Stoke City |
| 16 | Sat 3 Nov 2018 | 10-0 v MiddlesbroughStoke City 0-0 Middlesbrough |
| 17 | Sat 10 Nov 2018 | 10-0 v Nottingham ForestNottingham Forest 0-0 Stoke City |
| 18 | Sat 24 Nov 2018 | 12-2 v Queens Park RangersStoke City 2-2 Queens Park Rangers |
| 19 | Wed 28 Nov 2018 | 12-1 v Derby CountyStoke City 2-1 Derby County |
| 20 | Sat 1 Dec 2018 | 12-2 v ReadingReading 2-2 Stoke City |
| 21 | Sat 8 Dec 2018 | 12-0 v Ipswich TownStoke City 2-0 Ipswich Town |
| 22 | Sat 15 Dec 2018 | 12-2 v Aston VillaAston Villa 2-2 Stoke City |
| 23 | Sat 22 Dec 2018 | 11-0 v MillwallStoke City 1-0 Millwall |
| 24 | Wed 26 Dec 2018 | 10-2 v Birmingham CityBirmingham City 2-0 Stoke City |
| 25 | Sat 29 Dec 2018 | 10-0 v Bolton WanderersBolton Wanderers 0-0 Stoke City |
| 26 | Tue 1 Jan 2019 | 10-2 v Bristol CityStoke City 0-2 Bristol City |
| 27 | Sat 12 Jan 2019 | 11-3 v BrentfordBrentford 3-1 Stoke City |
| 28 | Sat 19 Jan 2019 | 12-1 v Leeds UnitedStoke City 2-1 Leeds United |
| 29 | Sat 26 Jan 2019 | 10-2 v Preston North EndStoke City 0-2 Preston North End |
| 30 | Sat 2 Feb 2019 | 10-2 v Hull CityHull City 2-0 Stoke City |
| 31 | Sat 9 Feb 2019 | 10-1 v West Bromwich AlbionStoke City 0-1 West Bromwich Albion |
| 32 | Wed 13 Feb 2019 | 10-0 v Wigan AthleticWigan Athletic 0-0 Stoke City |
| 33 | Sat 16 Feb 2019 | 11-1 v Ipswich TownIpswich Town 1-1 Stoke City |
| 34 | Sat 23 Feb 2019 | 11-1 v Aston VillaStoke City 1-1 Aston Villa |
| 35 | Sat 2 Mar 2019 | 12-0 v Nottingham ForestStoke City 2-0 Nottingham Forest |
| 36 | Sat 9 Mar 2019 | 10-0 v Queens Park RangersQueens Park Rangers 0-0 Stoke City |
| 37 | Wed 13 Mar 2019 | 10-0 v Derby CountyDerby County 0-0 Stoke City |
| 38 | Sat 16 Mar 2019 | 10-0 v ReadingStoke City 0-0 Reading |
| 39 | Sat 30 Mar 2019 | 10-0 v Sheffield WednesdayStoke City 0-0 Sheffield Wednesday |
| 40 | Sat 6 Apr 2019 | 11-0 v Blackburn RoversBlackburn Rovers 0-1 Stoke City |
| 41 | Tue 9 Apr 2019 | 11-3 v Swansea CitySwansea City 3-1 Stoke City |
| 42 | Sat 13 Apr 2019 | 12-2 v Rotherham UnitedStoke City 2-2 Rotherham United |
| 43 | Mon 22 Apr 2019 | 12-2 v Norwich CityStoke City 2-2 Norwich City |
| 44 | Sat 27 Apr 2019 | 10-0 v MillwallMillwall 0-0 Stoke City |
| 45 | Sun 5 May 2019 | 12-2 v Sheffield UnitedStoke City 2-2 Sheffield United |
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