| 1 | Sat 4 Aug 2018 | 41-2 v Swansea CitySheffield United 1-2 Swansea City |
| 2 | Tue 7 Aug 2018 | 40-3 v MiddlesbroughMiddlesbrough 3-0 Sheffield United |
| 3 | Sat 11 Aug 2018 | 42-1 v Queens Park RangersQueens Park Rangers 1-2 Sheffield United |
| 4 | Sat 18 Aug 2018 | 42-1 v Norwich CitySheffield United 2-1 Norwich City |
| 5 | Sat 25 Aug 2018 | 43-0 v Bolton WanderersBolton Wanderers 0-3 Sheffield United |
| 6 | Sat 1 Sep 2018 | 44-1 v Aston VillaSheffield United 4-1 Aston Villa |
| 7 | Wed 19 Sep 2018 | 40-0 v Birmingham CitySheffield United 0-0 Birmingham City |
| 8 | Sat 22 Sep 2018 | 43-2 v Preston North EndSheffield United 3-2 Preston North End |
| 9 | Sat 29 Sep 2018 | 43-2 v MillwallMillwall 2-3 Sheffield United |
| 10 | Wed 3 Oct 2018 | 42-0 v Blackburn RoversBlackburn Rovers 0-2 Sheffield United |
| 11 | Sat 6 Oct 2018 | 41-0 v Hull CitySheffield United 1-0 Hull City |
| 12 | Sat 20 Oct 2018 | 41-2 v Derby CountyDerby County 2-1 Sheffield United |
| 13 | Tue 23 Oct 2018 | 41-1 v Stoke CitySheffield United 1-1 Stoke City |
| 14 | Sat 27 Oct 2018 | 4 4-2 v Wigan AthleticSheffield United 4-2 Wigan Athletic |
| 15 | Sat 3 Nov 2018 | 40-1 v Nottingham ForestNottingham Forest 1-0 Sheffield United |
| 16 | Fri 9 Nov 2018 | 40-0 v Sheffield WednesdaySheffield United 0-0 Sheffield Wednesday |
| 17 | Sat 24 Nov 2018 | 42-2 v Rotherham UnitedRotherham United 2-2 Sheffield United |
| 18 | Tue 27 Nov 2018 | 43-2 v BrentfordBrentford 2-3 Sheffield United |
| 19 | Sat 1 Dec 2018 | 40-1 v Leeds UnitedSheffield United 0-1 Leeds United |
| 20 | Sat 8 Dec 2018 | 4 2-0 v ReadingReading 0-2 Sheffield United |
| 21 | Fri 14 Dec 2018 | 41-2 v West Bromwich AlbionSheffield United 1-2 West Bromwich Albion |
| 22 | Sat 22 Dec 2018 | 41-1 v Ipswich TownIpswich Town 1-1 Sheffield United |
| 23 | Wed 26 Dec 2018 | 43-1 v Derby CountySheffield United 3-1 Derby County |
| 24 | Sat 29 Dec 2018 | 43-0 v Blackburn RoversSheffield United 3-0 Blackburn Rovers |
| 25 | Tue 1 Jan 2019 | 4 3-0 v Wigan AthleticWigan Athletic 0-3 Sheffield United |
| 26 | Sat 12 Jan 2019 | 4 1-0 v Queens Park RangersSheffield United 1-0 Queens Park Rangers |
| 27 | Sat 19 Jan 2019 | 40-1 v Swansea CitySwansea City 1-0 Sheffield United |
| 28 | Sat 26 Jan 2019 | 42-2 v Norwich CityNorwich City 2-2 Sheffield United |
| 29 | Sat 2 Feb 2019 | 42-0 v Bolton WanderersSheffield United 2-0 Bolton Wanderers |
| 30 | Fri 8 Feb 2019 | 43-3 v Aston VillaAston Villa 3-3 Sheffield United |
| 31 | Wed 13 Feb 2019 | 4 1-0 v MiddlesbroughSheffield United 1-0 Middlesbrough |
| 32 | Sat 16 Feb 2019 | 44-0 v ReadingSheffield United 4-0 Reading |
| 33 | Sat 23 Feb 2019 | 41-0 v West Bromwich AlbionWest Bromwich Albion 0-1 Sheffield United |
| 34 | Mon 4 Mar 2019 | 40-0 v Sheffield WednesdaySheffield Wednesday 0-0 Sheffield United |
| 35 | Sat 9 Mar 2019 | 42-0 v Rotherham UnitedSheffield United 2-0 Rotherham United |
| 36 | Tue 12 Mar 2019 | 42-0 v BrentfordSheffield United 2-0 Brentford |
| 37 | Sat 16 Mar 2019 | 41-0 v Leeds UnitedLeeds United 0-1 Sheffield United |
| 38 | Sat 30 Mar 2019 | 42-3 v Bristol CitySheffield United 2-3 Bristol City |
| 39 | Sat 6 Apr 2019 | 41-0 v Preston North EndPreston North End 0-1 Sheffield United |
| 40 | Wed 10 Apr 2019 | 41-1 v Birmingham CityBirmingham City 1-1 Sheffield United |
| 41 | Sat 13 Apr 2019 | 4 1-1 v MillwallSheffield United 1-1 Millwall |
| 42 | Fri 19 Apr 2019 | 42-0 v Nottingham ForestSheffield United 2-0 Nottingham Forest |
| 43 | Mon 22 Apr 2019 | 43-0 v Hull CityHull City 0-3 Sheffield United |
| 44 | Sat 27 Apr 2019 | 42-0 v Ipswich TownSheffield United 2-0 Ipswich Town |
| 45 | Sun 5 May 2019 | 4 2-2 v Stoke CityStoke City 2-2 Sheffield United |
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