| 1 | Sat 7 Aug 2021 | 221-1 v MillwallQueens Park Rangers 1-1 Millwall |
| 2 | Sat 14 Aug 2021 | 223-0 v Hull CityHull City 0-3 Queens Park Rangers |
| 3 | Wed 18 Aug 2021 | 22 3-2 v MiddlesbroughMiddlesbrough 2-3 Queens Park Rangers |
| 4 | Sat 28 Aug 2021 | 222-0 v Coventry CityQueens Park Rangers 2-0 Coventry City |
| 5 | Sat 11 Sep 2021 | 223-3 v ReadingReading 3-3 Queens Park Rangers |
| 6 | Sat 18 Sep 2021 | 221-2 v Bristol CityQueens Park Rangers 1-2 Bristol City |
| 7 | Fri 24 Sep 2021 | 221-2 v West Bromwich AlbionWest Bromwich Albion 2-1 Queens Park Rangers |
| 8 | Tue 28 Sep 2021 | 222-0 v Birmingham CityQueens Park Rangers 2-0 Birmingham City |
| 9 | Sat 2 Oct 2021 | 223-2 v Preston North EndQueens Park Rangers 3-2 Preston North End |
| 10 | Sat 16 Oct 2021 | 22 1-4 v FulhamFulham 4-1 Queens Park Rangers |
| 11 | Fri 29 Oct 2021 | 221-1 v Nottingham ForestQueens Park Rangers 1-1 Nottingham Forest |
| 12 | Wed 3 Nov 2021 | 221-0 v Cardiff CityCardiff City 0-1 Queens Park Rangers |
| 13 | Sat 6 Nov 2021 | 22 1-1 v BlackpoolBlackpool 1-1 Queens Park Rangers |
| 14 | Mon 29 Nov 2021 | 222-1 v Derby CountyDerby County 1-2 Queens Park Rangers |
| 15 | Tue 25 Jan 2022 | 22 0-0 v Swansea CityQueens Park Rangers 0-0 Swansea City |
| 16 | Wed 9 Feb 2022 | 222-2 v MiddlesbroughQueens Park Rangers 2-2 Middlesbrough |
| 17 | Sat 12 Feb 2022 | 220-1 v BarnsleyBarnsley 1-0 Queens Park Rangers |
| 18 | Tue 15 Feb 2022 | 220-2 v MillwallMillwall 2-0 Queens Park Rangers |
| 19 | Sat 19 Feb 2022 | 221-1 v Hull CityQueens Park Rangers 1-1 Hull City |
| 20 | Wed 23 Feb 2022 | 222-1 v BlackpoolQueens Park Rangers 2-1 Blackpool |
| 21 | Sat 26 Feb 2022 | 220-1 v Blackburn RoversBlackburn Rovers 1-0 Queens Park Rangers |
| 22 | Sat 5 Mar 2022 | 221-2 v Cardiff CityQueens Park Rangers 1-2 Cardiff City |
| 23 | Sun 13 Mar 2022 | 222-1 v Luton TownLuton Town 1-2 Queens Park Rangers |
| 24 | Wed 16 Mar 2022 | 22 1-3 v Nottingham ForestNottingham Forest 3-1 Queens Park Rangers |
| 25 | Sat 2 Apr 2022 | 220-2 v FulhamQueens Park Rangers 0-2 Fulham |
| 26 | Sat 9 Apr 2022 | 221-2 v Preston North EndPreston North End 2-1 Queens Park Rangers |
| 27 | Fri 15 Apr 2022 | 222-2 v Huddersfield TownHuddersfield Town 2-2 Queens Park Rangers |
| 28 | Mon 18 Apr 2022 | 221-0 v Derby CountyQueens Park Rangers 1-0 Derby County |
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