| 1 | Sat 16 Jan 2021 | 52-0 v Heracles AlmeloFC Utrecht 2-0 Heracles Almelo |
| 2 | Sun 24 Jan 2021 | 51-0 v Sparta RotterdamFC Utrecht 1-0 Sparta Rotterdam |
| 3 | Wed 27 Jan 2021 | 51-0 v AZ AlkmaarAZ Alkmaar 0-1 FC Utrecht |
| 4 | Sat 30 Jan 2021 | 53-3 v PEC ZwolleFC Utrecht 3-3 PEC Zwolle |
| 5 | Sun 14 Feb 2021 | 53-1 v VVV VenloFC Utrecht 3-1 VVV Venlo |
| 6 | Fri 19 Feb 2021 | 56-0 v Willem IIWillem II 0-6 FC Utrecht |
| 7 | Sat 27 Feb 2021 | 50-1 v FC EmmenFC Utrecht 0-1 FC Emmen |
| 8 | Sat 6 Mar 2021 | 52-1 v RKC WaalwijkRKC Waalwijk 1-2 FC Utrecht |
| 9 | Sun 14 Mar 2021 | 51-3 v VitesseFC Utrecht 1-3 Vitesse |
| 10 | Sat 20 Mar 2021 | 51-0 v Fortuna SittardFortuna Sittard 0-1 FC Utrecht |
| 11 | Sun 4 Apr 2021 | 54-1 v ADO Den HaagADO Den Haag 1-4 FC Utrecht |
| 12 | Sun 11 Apr 2021 | 51-2 v FeyenoordFC Utrecht 1-2 Feyenoord |
| 13 | Thu 22 Apr 2021 | 51-1 v AjaxAjax 1-1 FC Utrecht |
| 14 | Sun 25 Apr 2021 | 52-1 v FC TwenteFC Twente 1-2 FC Utrecht |
| 15 | Sat 1 May 2021 | 53-2 v Willem IIFC Utrecht 3-2 Willem II |
| 16 | Sat 8 May 2021 | 50-0 v sc Heerenveensc Heerenveen 0-0 FC Utrecht |
| 17 | Thu 13 May 2021 | 50-0 v Sparta RotterdamSparta Rotterdam 0-0 FC Utrecht |
| 18 | Sun 16 May 2021 | 51-1 v PSV EindhovenFC Utrecht 1-1 PSV Eindhoven |
| 19 | Wed 19 May 2021 | 51-0 v FC GroningenFC Utrecht 1-0 FC Groningen |
| 20 | Sun 23 May 2021 | 50-2 v FeyenoordFeyenoord 2-0 FC Utrecht |
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