| 1 | Sun 20 Sep 2020 | 181-1 v FeyenoordFeyenoord 1-1 FC Twente |
| 2 | Sat 3 Oct 2020 | 181-1 v FC EmmenFC Twente 1-1 FC Emmen |
| 3 | Sat 17 Oct 2020 | 183-0 v Willem IIWillem II 0-3 FC Twente |
| 4 | Sun 22 Nov 2020 | 181-1 v PSV EindhovenFC Twente 1-1 PSV Eindhoven |
| 5 | Sat 9 Jan 2021 | 184-1 v FC EmmenFC Emmen 1-4 FC Twente |
| 6 | Sun 17 Jan 2021 | 301-1 v RKC WaalwijkRKC Waalwijk 1-1 Willem II |
| 7 | Fri 22 Jan 2021 | 30 1-3 v PEC ZwolleWillem II 1-3 PEC Zwolle |
| 8 | Thu 28 Jan 2021 | 301-3 v AjaxAjax 3-1 Willem II |
| 9 | Sun 31 Jan 2021 | 302-0 v FC EmmenWillem II 2-0 FC Emmen |
| 10 | Sun 14 Feb 2021 | 300-5 v FeyenoordFeyenoord 5-0 Willem II |
| 11 | Fri 19 Feb 2021 | 30 0-6 v FC UtrechtWillem II 0-6 FC Utrecht |
| 12 | Wed 24 Feb 2021 | 301-1 v ADO Den HaagWillem II 1-1 ADO Den Haag |
| 13 | Sat 6 Mar 2021 | 301-1 v FC TwenteFC Twente 1-1 Willem II |
| 14 | Sun 21 Mar 2021 | 300-0 v VitesseVitesse 0-0 Willem II |
| 15 | Sat 3 Apr 2021 | 300-1 v AZ AlkmaarWillem II 0-1 AZ Alkmaar |
| 16 | Sat 10 Apr 2021 | 300-4 v Heracles AlmeloHeracles Almelo 4-0 Willem II |
| 17 | Fri 23 Apr 2021 | 301-0 v RKC WaalwijkWillem II 1-0 RKC Waalwijk |
| 18 | Sat 1 May 2021 | 302-3 v FC UtrechtFC Utrecht 3-2 Willem II |
| 19 | Sun 9 May 2021 | 300-2 v PSV EindhovenWillem II 0-2 PSV Eindhoven |
| 20 | Thu 13 May 2021 | 30 4-1 v ADO Den HaagADO Den Haag 1-4 Willem II |
| 21 | Sun 16 May 2021 | 302-1 v Fortuna SittardWillem II 2-1 Fortuna Sittard |
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