| 1 | Sat 11 Sep 2021 | 54-1 v RB LeipzigRB Leipzig 1-4 Bayern Munich |
| 2 | Fri 24 Sep 2021 | 5 3-1 v Greuther FürthGreuther Fürth 1-3 Bayern Munich |
| 3 | Sat 23 Oct 2021 | 54-0 v 1899 HoffenheimBayern Munich 4-0 1899 Hoffenheim |
| 4 | Sat 30 Oct 2021 | 55-2 v 1. FC Union Berlin1. FC Union Berlin 2-5 Bayern Munich |
| 5 | Fri 19 Nov 2021 | 51-2 v FC AugsburgFC Augsburg 2-1 Bayern Munich |
| 6 | Sat 27 Nov 2021 | 51-0 v Arminia BielefeldBayern Munich 1-0 Arminia Bielefeld |
| 7 | Sat 4 Dec 2021 | 53-2 v Borussia DortmundBorussia Dortmund 2-3 Bayern Munich |
| 8 | Sat 11 Dec 2021 | 52-1 v Mainz 05Bayern Munich 2-1 Mainz 05 |
| 9 | Tue 14 Dec 2021 | 55-0 v VfB StuttgartVfB Stuttgart 0-5 Bayern Munich |
| 10 | Fri 17 Dec 2021 | 54-0 v VfL WolfsburgBayern Munich 4-0 VfL Wolfsburg |
| 11 | Fri 7 Jan 2022 | 51-2 v Borussia MönchengladbachBayern Munich 1-2 Borussia Mönchengladbach |
| 12 | Sat 15 Jan 2022 | 54-0 v 1. FC Köln1. FC Köln 0-4 Bayern Munich |
| 13 | Sun 23 Jan 2022 | 54-1 v Hertha BerlinHertha Berlin 1-4 Bayern Munich |
| 14 | Sat 5 Feb 2022 | 53-2 v RB LeipzigBayern Munich 3-2 RB Leipzig |
| 15 | Sat 12 Feb 2022 | 5 2-4 v VfL BochumVfL Bochum 4-2 Bayern Munich |
| 16 | Sun 20 Feb 2022 | 54-1 v Greuther FürthBayern Munich 4-1 Greuther Fürth |
| 17 | Sat 26 Feb 2022 | 51-0 v Eintracht FrankfurtEintracht Frankfurt 0-1 Bayern Munich |
| 18 | Sat 5 Mar 2022 | 51-1 v Bayer 04 LeverkusenBayern Munich 1-1 Bayer 04 Leverkusen |
| 19 | Sat 12 Mar 2022 | 51-1 v 1899 Hoffenheim1899 Hoffenheim 1-1 Bayern Munich |
| 20 | Sat 2 Apr 2022 | 54-1 v SC FreiburgSC Freiburg 1-4 Bayern Munich |
| 21 | Sat 9 Apr 2022 | 51-0 v FC AugsburgBayern Munich 1-0 FC Augsburg |
| 22 | Sun 17 Apr 2022 | 53-0 v Arminia BielefeldArminia Bielefeld 0-3 Bayern Munich |
| 23 | Sat 23 Apr 2022 | 53-1 v Borussia DortmundBayern Munich 3-1 Borussia Dortmund |
| 24 | Sat 30 Apr 2022 | 5 1-3 v Mainz 05Mainz 05 3-1 Bayern Munich |
| 25 | Sun 8 May 2022 | 52-2 v VfB StuttgartBayern Munich 2-2 VfB Stuttgart |
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