| 1 | Fri 13 Aug 2021 | 41-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-1 Bayern Munich |
| 2 | Sun 22 Aug 2021 | 4 3-2 v 1. FC KölnBayern Munich 3-2 1. FC Köln |
| 3 | Sat 28 Aug 2021 | 45-0 v Hertha BerlinBayern Munich 5-0 Hertha Berlin |
| 4 | Sat 11 Sep 2021 | 44-1 v RB LeipzigRB Leipzig 1-4 Bayern Munich |
| 5 | Sat 18 Sep 2021 | 47-0 v VfL BochumBayern Munich 7-0 VfL Bochum |
| 6 | Fri 24 Sep 2021 | 43-1 v Greuther FürthGreuther Fürth 1-3 Bayern Munich |
| 7 | Sun 3 Oct 2021 | 41-2 v Eintracht FrankfurtBayern Munich 1-2 Eintracht Frankfurt |
| 8 | Sun 17 Oct 2021 | 45-1 v Bayer 04 LeverkusenBayer 04 Leverkusen 1-5 Bayern Munich |
| 9 | Sat 23 Oct 2021 | 44-0 v 1899 HoffenheimBayern Munich 4-0 1899 Hoffenheim |
| 10 | Sat 30 Oct 2021 | 4 5-2 v 1. FC Union Berlin1. FC Union Berlin 2-5 Bayern Munich |
| 11 | Sat 6 Nov 2021 | 42-1 v SC FreiburgBayern Munich 2-1 SC Freiburg |
| 12 | Sat 27 Nov 2021 | 41-0 v Arminia BielefeldBayern Munich 1-0 Arminia Bielefeld |
| 13 | Sat 4 Dec 2021 | 43-2 v Borussia DortmundBorussia Dortmund 2-3 Bayern Munich |
| 14 | Sat 11 Dec 2021 | 42-1 v Mainz 05Bayern Munich 2-1 Mainz 05 |
| 15 | Tue 14 Dec 2021 | 45-0 v VfB StuttgartVfB Stuttgart 0-5 Bayern Munich |
| 16 | Fri 7 Jan 2022 | 41-2 v Borussia MönchengladbachBayern Munich 1-2 Borussia Mönchengladbach |
| 17 | Sat 15 Jan 2022 | 44-0 v 1. FC Köln1. FC Köln 0-4 Bayern Munich |
| 18 | Sun 23 Jan 2022 | 44-1 v Hertha BerlinHertha Berlin 1-4 Bayern Munich |
| 19 | Sat 5 Feb 2022 | 43-2 v RB LeipzigBayern Munich 3-2 RB Leipzig |
| 20 | Sat 12 Feb 2022 | 42-4 v VfL BochumVfL Bochum 4-2 Bayern Munich |
| 21 | Sun 20 Feb 2022 | 44-1 v Greuther FürthBayern Munich 4-1 Greuther Fürth |
| 22 | Sat 26 Feb 2022 | 41-0 v Eintracht FrankfurtEintracht Frankfurt 0-1 Bayern Munich |
| 23 | Sat 5 Mar 2022 | 41-1 v Bayer 04 LeverkusenBayern Munich 1-1 Bayer 04 Leverkusen |
| 24 | Sat 12 Mar 2022 | 41-1 v 1899 Hoffenheim1899 Hoffenheim 1-1 Bayern Munich |
| 25 | Sat 2 Apr 2022 | 44-1 v SC FreiburgSC Freiburg 1-4 Bayern Munich |
| 26 | Sat 23 Apr 2022 | 43-1 v Borussia DortmundBayern Munich 3-1 Borussia Dortmund |
| 27 | Sat 30 Apr 2022 | 41-3 v Mainz 05Mainz 05 3-1 Bayern Munich |
| 28 | Sun 8 May 2022 | 42-2 v VfB StuttgartBayern Munich 2-2 VfB Stuttgart |
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