| 1 | Sat 19 Aug | 111-2 v SC Freiburg1899 Hoffenheim 1-2 SC Freiburg |
| 2 | Sat 26 Aug | 11 3-2 v 1 FC Heidenheim1 FC Heidenheim 2-3 1899 Hoffenheim |
| 3 | Sat 2 Sep | 113-1 v VfL Wolfsburg1899 Hoffenheim 3-1 VfL Wolfsburg |
| 4 | Sat 16 Sep | 11 3-1 v 1 FC Köln1 FC Köln 1-3 1899 Hoffenheim |
| 5 | Fri 29 Sep | 111-3 v Borussia Dortmund1899 Hoffenheim 1-3 Borussia Dortmund |
| 6 | Sat 7 Oct | 113-2 v Werder BremenWerder Bremen 2-3 1899 Hoffenheim |
| 7 | Sat 21 Oct | 11 1-3 v Eintracht Frankfurt1899 Hoffenheim 1-3 Eintracht Frankfurt |
| 8 | Sat 28 Oct | 113-2 v VfB StuttgartVfB Stuttgart 2-3 1899 Hoffenheim |
| 9 | Sun 26 Nov | 111-1 v Mainz 051899 Hoffenheim 1-1 Mainz 05 |
| 10 | Sat 2 Dec | 111-2 v Borussia MönchengladbachBorussia Mönchengladbach 2-1 1899 Hoffenheim |
| 11 | Fri 8 Dec | 113-1 v VfL Bochum1899 Hoffenheim 3-1 VfL Bochum |
| 12 | Sat 16 Dec | 11 1-3 v RB LeipzigRB Leipzig 3-1 1899 Hoffenheim |
| 13 | Tue 19 Dec | 113-3 v Darmstadt 981899 Hoffenheim 3-3 Darmstadt 98 |
| 14 | Fri 12 Jan | 110-3 v Bayern MunichBayern Munich 3-0 1899 Hoffenheim |
| 15 | Sat 20 Jan | 112-3 v SC FreiburgSC Freiburg 3-2 1899 Hoffenheim |
| 16 | Sat 27 Jan | 11 1-1 v 1 FC Heidenheim1899 Hoffenheim 1-1 1 FC Heidenheim |
| 17 | Sun 11 Feb | 11 1-1 v 1 FC Köln1899 Hoffenheim 1-1 1 FC Köln |
| 18 | Sat 17 Feb | 110-1 v 1 FC Union Berlin1899 Hoffenheim 0-1 1 FC Union Berlin |
| 19 | Sun 25 Feb | 113-2 v Borussia DortmundBorussia Dortmund 2-3 1899 Hoffenheim |
| 20 | Sun 3 Mar | 11 2-1 v Werder Bremen1899 Hoffenheim 2-1 Werder Bremen |
| 21 | Sun 10 Mar | 111-3 v Eintracht FrankfurtEintracht Frankfurt 3-1 1899 Hoffenheim |
| 22 | Sat 16 Mar | 110-3 v VfB Stuttgart1899 Hoffenheim 0-3 VfB Stuttgart |
| 23 | Sat 30 Mar | 111-2 v Bayer 04 LeverkusenBayer 04 Leverkusen 2-1 1899 Hoffenheim |
| 24 | Sun 7 Apr | 113-1 v FC Augsburg1899 Hoffenheim 3-1 FC Augsburg |
| 25 | Sat 13 Apr | 111-4 v Mainz 05Mainz 05 4-1 1899 Hoffenheim |
| 26 | Sat 20 Apr | 114-3 v Borussia Mönchengladbach1899 Hoffenheim 4-3 Borussia Mönchengladbach |
| 27 | Fri 26 Apr | 112-3 v VfL BochumVfL Bochum 3-2 1899 Hoffenheim |
| 28 | Fri 3 May | 111-1 v RB Leipzig1899 Hoffenheim 1-1 RB Leipzig |
| 29 | Sun 12 May | 116-0 v Darmstadt 98Darmstadt 98 0-6 1899 Hoffenheim |
| 30 | Sat 18 May | 11 4-2 v Bayern Munich1899 Hoffenheim 4-2 Bayern Munich |
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