| 1 | Fri 25 Aug | 165-1 v VfB StuttgartRB Leipzig 5-1 VfB Stuttgart |
| 2 | Sun 3 Sep | 163-0 v 1 FC Union Berlin1 FC Union Berlin 0-3 RB Leipzig |
| 3 | Sat 23 Sep | 161-0 v Borussia MönchengladbachBorussia Mönchengladbach 0-1 RB Leipzig |
| 4 | Sat 30 Sep | 162-2 v Bayern MunichRB Leipzig 2-2 Bayern Munich |
| 5 | Sat 7 Oct | 160-0 v VfL BochumRB Leipzig 0-0 VfL Bochum |
| 6 | Sat 21 Oct | 163-1 v Darmstadt 98Darmstadt 98 1-3 RB Leipzig |
| 7 | Sat 28 Oct | 16 6-0 v 1 FC KölnRB Leipzig 6-0 1 FC Köln |
| 8 | Sat 4 Nov | 16 0-2 v Mainz 05Mainz 05 2-0 RB Leipzig |
| 9 | Sun 12 Nov | 163-1 v SC FreiburgRB Leipzig 3-1 SC Freiburg |
| 10 | Sat 2 Dec | 162-1 v 1 FC HeidenheimRB Leipzig 2-1 1 FC Heidenheim |
| 11 | Sat 9 Dec | 163-2 v Borussia DortmundBorussia Dortmund 2-3 RB Leipzig |
| 12 | Sat 16 Dec | 16 3-1 v 1899 HoffenheimRB Leipzig 3-1 1899 Hoffenheim |
| 13 | Tue 19 Dec | 161-1 v Werder BremenWerder Bremen 1-1 RB Leipzig |
| 14 | Sat 13 Jan | 160-1 v Eintracht FrankfurtRB Leipzig 0-1 Eintracht Frankfurt |
| 15 | Sat 20 Jan | 162-3 v Bayer 04 LeverkusenRB Leipzig 2-3 Bayer 04 Leverkusen |
| 16 | Sat 27 Jan | 162-5 v VfB StuttgartVfB Stuttgart 5-2 RB Leipzig |
| 17 | Sun 4 Feb | 162-0 v 1 FC Union BerlinRB Leipzig 2-0 1 FC Union Berlin |
| 18 | Sat 10 Feb | 162-2 v FC AugsburgFC Augsburg 2-2 RB Leipzig |
| 19 | Sat 17 Feb | 162-0 v Borussia MönchengladbachRB Leipzig 2-0 Borussia Mönchengladbach |
| 20 | Sat 6 Apr | 164-1 v SC FreiburgSC Freiburg 1-4 RB Leipzig |
| 21 | Sat 13 Apr | 163-0 v VfL WolfsburgRB Leipzig 3-0 VfL Wolfsburg |
| 22 | Sat 20 Apr | 162-1 v 1 FC Heidenheim1 FC Heidenheim 1-2 RB Leipzig |
| 23 | Sat 27 Apr | 164-1 v Borussia DortmundRB Leipzig 4-1 Borussia Dortmund |
| 24 | Sat 11 May | 161-1 v Werder BremenRB Leipzig 1-1 Werder Bremen |
| 25 | Sat 18 May | 162-2 v Eintracht FrankfurtEintracht Frankfurt 2-2 RB Leipzig |
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