| 1 | Sat 10 Aug | 160-1 v Fleetwood TownFleetwood Town 1-0 Grimsby Town | Sky Bet League Two |
| 2 | Tue 13 Aug | 161-1 v Bradford CityGrimsby Town 1-1 Bradford City | Carabao Cup First Round |
| 3 | Sat 17 Aug | 163-2 v Cheltenham TownGrimsby Town 3-2 Cheltenham Town | Sky Bet League Two |
| 4 | Thu 22 Aug | 161-4 v Notts CountyNotts County 4-1 Grimsby Town | Sky Bet League Two |
| 5 | Tue 27 Aug | 161-5 v Sheffield WednesdayGrimsby Town 1-5 Sheffield Wednesday | Carabao Cup Second Round |
| 6 | Sat 31 Aug | 162-1 v Bradford CityGrimsby Town 2-1 Bradford City | Sky Bet League Two |
| 7 | Sat 7 Sep | 161-2 v ChesterfieldChesterfield 2-1 Grimsby Town | Sky Bet League Two |
| 8 | Sat 14 Sep | 16 1-2 v BarrowGrimsby Town 1-2 Barrow | Sky Bet League Two |
| 9 | Sat 28 Sep | 163-2 v Carlisle UnitedCarlisle United 2-3 Grimsby Town | Sky Bet League Two |
| 10 | Tue 8 Oct | 16 1-2 v Lincoln CityGrimsby Town 1-2 Lincoln City | EFL Trophy Northern Group G |
| 11 | Sat 12 Oct | 162-1 v Salford CitySalford City 1-2 Grimsby Town | Sky Bet League Two |
| 12 | Sat 19 Oct | 161-4 v WalsallGrimsby Town 1-4 Walsall | Sky Bet League Two |
| 13 | Tue 22 Oct | 161-0 v Tranmere RoversTranmere Rovers 0-1 Grimsby Town | Sky Bet League Two |
| 14 | Sat 9 Nov | 161-0 v AFC WimbledonAFC Wimbledon 0-1 Grimsby Town | Sky Bet League Two |
| 15 | Tue 12 Nov | 162-3 v ChesterfieldChesterfield 3-2 Grimsby Town | EFL Trophy Northern Group G |
| 16 | Sat 23 Nov | 160-1 v Colchester UnitedGrimsby Town 0-1 Colchester United | Sky Bet League Two |
| 17 | Tue 3 Dec | 165-2 v Accrington StanleyGrimsby Town 5-2 Accrington Stanley | Sky Bet League Two |
| 18 | Sat 7 Dec | 163-0 v MorecambeMorecambe 0-3 Grimsby Town | Sky Bet League Two |
| 19 | Thu 26 Dec | 162-1 v Harrogate TownGrimsby Town 2-1 Harrogate Town | Sky Bet League Two |
| 20 | Sun 29 Dec | 163-0 v Port ValeGrimsby Town 3-0 Port Vale | Sky Bet League Two |
| 21 | Wed 1 Jan | 162-3 v Accrington StanleyAccrington Stanley 3-2 Grimsby Town | Sky Bet League Two |
| 22 | Sat 4 Jan | 161-3 v Bradford CityBradford City 3-1 Grimsby Town | Sky Bet League Two |
| 23 | Sat 1 Feb | 162-0 v BromleyBromley 0-2 Grimsby Town | Sky Bet League Two |
| 24 | Sat 15 Feb | 162-1 v Doncaster RoversDoncaster Rovers 1-2 Grimsby Town | Sky Bet League Two |
| 25 | Sat 22 Feb | 162-1 v Fleetwood TownGrimsby Town 2-1 Fleetwood Town | Sky Bet League Two |
| 26 | Sat 8 Mar | 163-1 v WalsallWalsall 1-3 Grimsby Town | Sky Bet League Two |
| 27 | Tue 11 Mar | 160-2 v Notts CountyGrimsby Town 0-2 Notts County | Sky Bet League Two |
| 28 | Fri 18 Apr | 160-4 v Swindon TownGrimsby Town 0-4 Swindon Town | Sky Bet League Two |
| 29 | Mon 21 Apr | 162-2 v Port ValePort Vale 2-2 Grimsby Town | Sky Bet League Two |
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