| 1 | Sat 27 Jul | 73-1 v Northallerton TownNorthallerton Town 1-3 Guisborough Town | Northern League Division One |
| 2 | Tue 30 Jul | 70-1 v Kendal TownKendal Town 1-0 Guisborough Town | Northern League Division One |
| 3 | Sat 3 Aug | 72-2 v Kendal TownKendal Town 2-2 Guisborough Town | Emirates FA Cup Extra Preliminary Round |
| 4 | Wed 7 Aug | 81-2 v Kendal TownGuisborough Town 1-2 Kendal Town | Emirates FA Cup Extra Preliminary Round Replay |
| 5 | Sat 10 Aug | 72-0 v Newcastle Blue StarNewcastle Blue Star 0-2 Guisborough Town | Northern League Division One |
| 6 | Wed 14 Aug | 70-3 v Crook TownGuisborough Town 0-3 Crook Town | Northern League Division One |
| 7 | Sat 24 Aug | 71-1 v Redcar AthleticGuisborough Town 1-1 Redcar Athletic | Northern League Division One |
| 8 | Wed 28 Aug | 75-1 v Birtley TownGuisborough Town 5-1 Birtley Town | Northern League Division One |
| 9 | Sat 31 Aug | 73-0 v Easington CollieryEasington Colliery 0-3 Guisborough Town | Northern League Division One |
| 10 | Wed 4 Sep | 72-1 v PenrithGuisborough Town 2-1 Penrith | Northern League Division One |
| 11 | Sat 7 Sep | 70-4 v West Auckland TownGuisborough Town 0-4 West Auckland Town | Northern League Division One |
| 12 | Sat 14 Sep | 70-0 v West Allotment CelticWest Allotment Celtic 0-0 Guisborough Town | Northern League Division One |
| 13 | Tue 17 Sep | 82-2 v Tow Law TownTow Law Town 2-2 Guisborough Town | Northern League Division One |
| 14 | Sat 21 Sep | 8 2-1 v ShildonGuisborough Town 2-1 Shildon | Isuzu FA Vase Second Qualifying Round |
| 15 | Sat 28 Sep | 83-2 v Whitley BayGuisborough Town 3-2 Whitley Bay | Northern League Division One |
| 16 | Sat 12 Oct | 103-2 v Seaham Red StarGuisborough Town 3-2 Seaham Red Star | Northern League Division One |
| 17 | Sat 19 Oct | 100-1 v Carlisle CityGuisborough Town 0-1 Carlisle City | Isuzu FA Vase First Round |
| 18 | Wed 23 Oct | 81-3 v North ShieldsNorth Shields 3-1 Guisborough Town | Northern League Division One |
| 19 | Sat 26 Oct | 43-0 v Newcastle BenfieldGuisborough Town 3-0 Newcastle Benfield | Northern League Division One |
| 20 | Tue 29 Oct | 44-0 v WhickhamWhickham 0-4 Guisborough Town | Northern League Division One |
| 21 | Sat 2 Nov | 41-1 v Marske UnitedMarske United 1-1 Guisborough Town | Northern League Division One |
| 22 | Sat 9 Nov | 43-2 v Kendal TownGuisborough Town 3-2 Kendal Town | Northern League Division One |
| 23 | Sat 16 Nov | 43-2 v WhickhamGuisborough Town 3-2 Whickham | Northern League Division One |
| 24 | Sat 30 Nov | 4 0-0 v Carlisle CityGuisborough Town 0-0 Carlisle City | Northern League Division One |
| 25 | Wed 4 Dec | 41-1 v Crook TownCrook Town 1-1 Guisborough Town | Northern League Division One |
| 26 | Fri 13 Dec | 41-1 v Birtley TownBirtley Town 1-1 Guisborough Town | Northern League Division One |
| 27 | Sat 21 Dec | 42-0 v PenrithPenrith 0-2 Guisborough Town | Northern League Division One |
| 28 | Thu 26 Dec | 42-3 v Boro RangersGuisborough Town 2-3 Boro Rangers | Northern League Division One |
| 29 | Sat 28 Dec | 44-1 v Tow Law TownGuisborough Town 4-1 Tow Law Town | Northern League Division One |
| 30 | Sat 4 Jan | 44-0 v Boro RangersBoro Rangers 0-4 Guisborough Town | Northern League Division One |
| 31 | Sat 18 Jan | 40-2 v Redcar AthleticRedcar Athletic 2-0 Guisborough Town | Northern League Division One |
| 32 | Sat 25 Jan | 40-1 v Newcastle Blue StarGuisborough Town 0-1 Newcastle Blue Star | Northern League Division One |
| 33 | Sat 15 Feb | 81-4 v West Auckland TownWest Auckland Town 4-1 Guisborough Town | Northern League Division One |
| 34 | Sat 22 Feb | 80-0 v West Allotment CelticGuisborough Town 0-0 West Allotment Celtic | Northern League Division One |
| 35 | Wed 26 Feb | 41-2 v Northallerton TownGuisborough Town 1-2 Northallerton Town | Northern League Division One |
| 36 | Sat 1 Mar | 73-1 v Blyth TownBlyth Town 1-3 Guisborough Town | Northern League Division One |
| 37 | Sat 8 Mar | 71-1 v Whitley BayWhitley Bay 1-1 Guisborough Town | Northern League Division One |
| 38 | Sat 22 Mar | 80-0 v Seaham Red StarSeaham Red Star 0-0 Guisborough Town | Northern League Division One |
| 39 | Sat 29 Mar | 41-1 v ShildonGuisborough Town 1-1 Shildon | Northern League Division One |
| 40 | Sat 5 Apr | 8 2-1 v North ShieldsGuisborough Town 2-1 North Shields | Northern League Division One |
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