| 1 | Sat 6 Jul | 80-7 v Huddersfield TownGuiseley 0-7 Huddersfield Town | Friendly |
| 2 | Sat 13 Jul | 82-1 v Bradford CityGuiseley 2-1 Bradford City | Friendly |
| 3 | Tue 30 Jul | 40-4 v BarnsleyGuiseley 0-4 Barnsley | Friendly |
| 4 | Sat 10 Aug | 152-0 v Workington AFCGuiseley 2-0 Workington AFC | Northern Premier League - Premier Division |
| 5 | Wed 14 Aug | 151-3 v Stockton TownStockton Town 3-1 Guiseley | Northern Premier League - Premier Division |
| 6 | Sat 17 Aug | 8 1-3 v MacclesfieldMacclesfield 3-1 Guiseley | Northern Premier League - Premier Division |
| 7 | Tue 20 Aug | 80-0 v Blyth SpartansGuiseley 0-0 Blyth Spartans | Northern Premier League - Premier Division |
| 8 | Sat 24 Aug | 83-2 v FC United of ManchesterGuiseley 3-2 FC United of Manchester | Northern Premier League - Premier Division |
| 9 | Mon 26 Aug | 83-2 v Bamber BridgeBamber Bridge 2-3 Guiseley | Northern Premier League - Premier Division |
| 10 | Sat 31 Aug | 83-0 v Ashton UnitedGuiseley 3-0 Ashton United | Emirates FA Cup First Qualifying Round |
| 11 | Sat 7 Sep | 84-0 v Hyde UnitedGuiseley 4-0 Hyde United | Northern Premier League - Premier Division |
| 12 | Tue 10 Sep | 82-1 v Whitby TownWhitby Town 1-2 Guiseley | Northern Premier League - Premier Division |
| 13 | Sat 14 Sep | 143-0 v 1874 NorthwichGuiseley 3-0 1874 Northwich | Emirates FA Cup Second Qualifying Round |
| 14 | Tue 17 Sep | 83-3 v Morpeth TownGuiseley 3-3 Morpeth Town | Northern Premier League - Premier Division |
| 15 | Sat 21 Sep | 8 1-2 v Worksop TownGuiseley 1-2 Worksop Town | Northern Premier League - Premier Division |
| 16 | Tue 1 Oct | 82-0 v Basford UnitedBasford United 0-2 Guiseley | Northern Premier League - Premier Division |
| 17 | Sat 5 Oct | 40-1 v Bamber BridgeGuiseley 0-1 Bamber Bridge | Isuzu FA Trophy Third Qualifying Round |
| 18 | Sat 12 Oct | 81-0 v Kidderminster HarriersKidderminster Harriers 0-1 Guiseley | Emirates FA Cup Fourth Qualifying Round |
| 19 | Tue 15 Oct | 81-1 v Lancaster CityLancaster City 1-1 Guiseley | Northern Premier League - Premier Division |
| 20 | Sat 19 Oct | 81-1 v Ilkeston TownIlkeston Town 1-1 Guiseley | Northern Premier League - Premier Division |
| 21 | Sat 2 Nov | 8 1-1 v StevenageStevenage 1-1 Guiseley | Emirates FA Cup First Round |
| 22 | Sat 9 Nov | 81-0 v MickleoverMickleover 0-1 Guiseley | Northern Premier League - Premier Division |
| 23 | Tue 12 Nov | 82-0 v Prescot CablesGuiseley 2-0 Prescot Cables | Northern Premier League - Premier Division |
| 24 | Sat 16 Nov | 82-0 v Hebburn TownGuiseley 2-0 Hebburn Town | Northern Premier League - Premier Division |
| 25 | Tue 19 Nov | 84-2 v Ashton UnitedAshton United 2-4 Guiseley | Northern Premier League - Premier Division |
| 26 | Sat 30 Nov | 8 2-2 v Warrington RylandsGuiseley 2-2 Warrington Rylands | Northern Premier League - Premier Division |
| 27 | Sat 7 Dec | 83-1 v Whitby TownGuiseley 3-1 Whitby Town | Northern Premier League - Premier Division |
| 28 | Tue 10 Dec | 151-1 v Leek TownGuiseley 1-1 Leek Town | Northern Premier League - Premier Division |
| 29 | Sat 14 Dec | 81-1 v Hyde UnitedHyde United 1-1 Guiseley | Northern Premier League - Premier Division |
| 30 | Sat 21 Dec | 81-1 v Stockton TownGuiseley 1-1 Stockton Town | Northern Premier League - Premier Division |
| 31 | Thu 26 Dec | 82-0 v Gainsborough TrinityGainsborough Trinity 0-2 Guiseley | Northern Premier League - Premier Division |
| 32 | Wed 1 Jan | 83-1 v Bamber BridgeGuiseley 3-1 Bamber Bridge | Northern Premier League - Premier Division |
| 33 | Sat 4 Jan | 82-0 v Workington AFCWorkington AFC 0-2 Guiseley | Northern Premier League - Premier Division |
| 34 | Sat 18 Jan | 8 1-0 v Basford UnitedGuiseley 1-0 Basford United | Northern Premier League - Premier Division |
| 35 | Sat 25 Jan | 84-1 v Worksop TownWorksop Town 1-4 Guiseley | Northern Premier League - Premier Division |
| 36 | Tue 28 Jan | 80-2 v Morpeth TownMorpeth Town 2-0 Guiseley | Northern Premier League - Premier Division |
| 37 | Sat 1 Feb | 81-2 v Lancaster CityGuiseley 1-2 Lancaster City | Northern Premier League - Premier Division |
| 38 | Sat 8 Feb | 80-2 v Prescot CablesPrescot Cables 2-0 Guiseley | Northern Premier League - Premier Division |
| 39 | Sat 15 Feb | 81-1 v Ilkeston TownGuiseley 1-1 Ilkeston Town | Northern Premier League - Premier Division |
| 40 | Sat 22 Feb | 142-2 v Leek TownLeek Town 2-2 Guiseley | Northern Premier League - Premier Division |
| 41 | Sat 1 Mar | 81-0 v Ashton UnitedGuiseley 1-0 Ashton United | Northern Premier League - Premier Division |
| 42 | Sat 8 Mar | 80-0 v Matlock TownMatlock Town 0-0 Guiseley | Northern Premier League - Premier Division |
| 43 | Sat 15 Mar | 83-0 v MickleoverGuiseley 3-0 Mickleover | Northern Premier League - Premier Division |
| 44 | Sat 22 Mar | 81-0 v Hebburn TownHebburn Town 0-1 Guiseley | Northern Premier League - Premier Division |
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