| 1 | Sat 6 Jul | 60-7 v Huddersfield TownGuiseley 0-7 Huddersfield Town | Friendly |
| 2 | Sat 27 Jul | 61-0 v Leeds UnitedGuiseley 1-0 Leeds United | Friendly |
| 3 | Tue 30 Jul | 60-4 v BarnsleyGuiseley 0-4 Barnsley | Friendly |
| 4 | Sat 10 Aug | 62-0 v Workington AFCGuiseley 2-0 Workington AFC | Northern Premier League - Premier Division |
| 5 | Wed 14 Aug | 61-3 v Stockton TownStockton Town 3-1 Guiseley | Northern Premier League - Premier Division |
| 6 | Sat 17 Aug | 61-3 v MacclesfieldMacclesfield 3-1 Guiseley | Northern Premier League - Premier Division |
| 7 | Sat 24 Aug | 153-2 v FC United of ManchesterGuiseley 3-2 FC United of Manchester | Northern Premier League - Premier Division |
| 8 | Sat 7 Sep | 164-0 v Hyde UnitedGuiseley 4-0 Hyde United | Northern Premier League - Premier Division |
| 9 | Tue 10 Sep | 62-1 v Whitby TownWhitby Town 1-2 Guiseley | Northern Premier League - Premier Division |
| 10 | Sat 14 Sep | 63-0 v 1874 NorthwichGuiseley 3-0 1874 Northwich | Emirates FA Cup Second Qualifying Round |
| 11 | Tue 17 Sep | 63-3 v Morpeth TownGuiseley 3-3 Morpeth Town | Northern Premier League - Premier Division |
| 12 | Sat 21 Sep | 61-2 v Worksop TownGuiseley 1-2 Worksop Town | Northern Premier League - Premier Division |
| 13 | Sat 28 Sep | 61-0 v Scunthorpe UnitedGuiseley 1-0 Scunthorpe United | Emirates FA Cup Third Qualifying Round |
| 14 | Tue 1 Oct | 62-0 v Basford UnitedBasford United 0-2 Guiseley | Northern Premier League - Premier Division |
| 15 | Sat 5 Oct | 6 0-1 v Bamber BridgeGuiseley 0-1 Bamber Bridge | Isuzu FA Trophy Third Qualifying Round |
| 16 | Sat 12 Oct | 61-0 v Kidderminster HarriersKidderminster Harriers 0-1 Guiseley | Emirates FA Cup Fourth Qualifying Round |
| 17 | Tue 15 Oct | 61-1 v Lancaster CityLancaster City 1-1 Guiseley | Northern Premier League - Premier Division |
| 18 | Sat 19 Oct | 61-1 v Ilkeston TownIlkeston Town 1-1 Guiseley | Northern Premier League - Premier Division |
| 19 | Sat 2 Nov | 61-1 v StevenageStevenage 1-1 Guiseley | Emirates FA Cup First Round |
| 20 | Sat 9 Nov | 61-0 v MickleoverMickleover 0-1 Guiseley | Northern Premier League - Premier Division |
| 21 | Tue 12 Nov | 62-0 v Prescot CablesGuiseley 2-0 Prescot Cables | Northern Premier League - Premier Division |
| 22 | Sat 16 Nov | 62-0 v Hebburn TownGuiseley 2-0 Hebburn Town | Northern Premier League - Premier Division |
| 23 | Tue 19 Nov | 64-2 v Ashton UnitedAshton United 2-4 Guiseley | Northern Premier League - Premier Division |
| 24 | Sat 30 Nov | 62-2 v Warrington RylandsGuiseley 2-2 Warrington Rylands | Northern Premier League - Premier Division |
| 25 | Sat 7 Dec | 63-1 v Whitby TownGuiseley 3-1 Whitby Town | Northern Premier League - Premier Division |
| 26 | Tue 10 Dec | 61-1 v Leek TownGuiseley 1-1 Leek Town | Northern Premier League - Premier Division |
| 27 | Sat 14 Dec | 61-1 v Hyde UnitedHyde United 1-1 Guiseley | Northern Premier League - Premier Division |
| 28 | Sat 21 Dec | 61-1 v Stockton TownGuiseley 1-1 Stockton Town | Northern Premier League - Premier Division |
| 29 | Thu 26 Dec | 62-0 v Gainsborough TrinityGainsborough Trinity 0-2 Guiseley | Northern Premier League - Premier Division |
| 30 | Wed 1 Jan | 63-1 v Bamber BridgeGuiseley 3-1 Bamber Bridge | Northern Premier League - Premier Division |
| 31 | Sat 4 Jan | 62-0 v Workington AFCWorkington AFC 0-2 Guiseley | Northern Premier League - Premier Division |
| 32 | Sat 18 Jan | 61-0 v Basford UnitedGuiseley 1-0 Basford United | Northern Premier League - Premier Division |
| 33 | Sat 1 Feb | 151-2 v Lancaster CityGuiseley 1-2 Lancaster City | Northern Premier League - Premier Division |
| 34 | Sat 8 Feb | 60-2 v Prescot CablesPrescot Cables 2-0 Guiseley | Northern Premier League - Premier Division |
| 35 | Sat 15 Feb | 61-1 v Ilkeston TownGuiseley 1-1 Ilkeston Town | Northern Premier League - Premier Division |
| 36 | Sat 22 Feb | 62-2 v Leek TownLeek Town 2-2 Guiseley | Northern Premier League - Premier Division |
| 37 | Sat 1 Mar | 61-0 v Ashton UnitedGuiseley 1-0 Ashton United | Northern Premier League - Premier Division |
| 38 | Sat 8 Mar | 60-0 v Matlock TownMatlock Town 0-0 Guiseley | Northern Premier League - Premier Division |
| 39 | Sat 15 Mar | 63-0 v MickleoverGuiseley 3-0 Mickleover | Northern Premier League - Premier Division |
| 40 | Sat 22 Mar | 61-0 v Hebburn TownHebburn Town 0-1 Guiseley | Northern Premier League - Premier Division |
| 41 | Sat 5 Apr | 61-1 v Warrington RylandsWarrington Rylands 1-1 Guiseley | Northern Premier League - Premier Division |
| 42 | Sat 12 Apr | 60-3 v MacclesfieldGuiseley 0-3 Macclesfield | Northern Premier League - Premier Division |
| 43 | Sat 19 Apr | 62-0 v Blyth SpartansBlyth Spartans 0-2 Guiseley | Northern Premier League - Premier Division |
| 44 | Sat 26 Apr | 61-1 v FC United of ManchesterFC United of Manchester 1-1 Guiseley | Northern Premier League - Premier Division |
| 45 | Tue 29 Apr | 60-1 v Stockton TownStockton Town 1-0 Guiseley | Northern Premier League - Premier Division Play-off Semi Final |
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