| 1 | Sat 14 Aug 2021 | 5 3-2 v Great Wakering RoversGreat Wakering Rovers 2-3 Witham Town |
| 2 | Sat 11 Sep 2021 | 4 0-2 v RomfordWitham Town 0-2 Romford |
| 3 | Tue 14 Sep 2021 | 21-1 v Basildon UnitedBasildon United 1-1 Witham Town |
| 4 | Tue 28 Sep 2021 | 20-1 v Hashtag UnitedWitham Town 0-1 Hashtag United |
| 5 | Sat 16 Oct 2021 | 3 1-3 v Dereham TownDereham Town 3-1 Witham Town |
| 6 | Tue 19 Oct 2021 | 51-1 v BarkingBarking 1-1 Witham Town |
| 7 | Sat 23 Oct 2021 | 51-1 v Coggeshall TownWitham Town 1-1 Coggeshall Town |
| 8 | Tue 2 Nov 2021 | 20-6 v Canvey IslandCanvey Island 6-0 Witham Town |
| 9 | Fri 5 Nov 2021 | 20-3 v Maldon & TiptreeWitham Town 0-3 Maldon & Tiptree |
| 10 | Sat 20 Nov 2021 | 21-1 v Grays AthleticWitham Town 1-1 Grays Athletic |
| 11 | Sat 27 Nov 2021 | 22-4 v AveleyAveley 4-2 Witham Town |
| 12 | Sat 4 Dec 2021 | 20-4 v Brentwood TownWitham Town 0-4 Brentwood Town |
| 13 | Sat 11 Dec 2021 | 61-2 v Great Wakering RoversWitham Town 1-2 Great Wakering Rovers |
| 14 | Tue 14 Dec 2021 | 51-1 v Felixstowe & Walton UnitedFelixstowe & Walton United 1-1 Witham Town |
| 15 | Sat 18 Dec 2021 | 50-0 v TilburyTilbury 0-0 Witham Town |
| 16 | Mon 27 Dec 2021 | 50-1 v Hullbridge SportsWitham Town 0-1 Hullbridge Sports |
| 17 | Sat 1 Jan 2022 | 32-2 v Heybridge SwiftsHeybridge Swifts 2-2 Witham Town |
| 18 | Sat 8 Jan 2022 | 42-3 v Stowmarket TownStowmarket Town 3-2 Witham Town |
| 19 | Sat 15 Jan 2022 | 52-1 v Bury TownBury Town 1-2 Witham Town |
| 20 | Sat 22 Jan 2022 | 50-0 v Basildon UnitedWitham Town 0-0 Basildon United |
| 21 | Sat 29 Jan 2022 | 51-5 v Hashtag UnitedHashtag United 5-1 Witham Town |
| 22 | Sat 5 Feb 2022 | 30-0 v BarkingWitham Town 0-0 Barking |
| 23 | Sat 12 Feb 2022 | 50-1 v Dereham TownWitham Town 0-1 Dereham Town |
| 24 | Sat 26 Feb 2022 | 50-1 v Canvey IslandWitham Town 0-1 Canvey Island |
| 25 | Fri 4 Mar 2022 | 21-0 v Maldon & TiptreeMaldon & Tiptree 0-1 Witham Town |
| 26 | Tue 8 Mar 2022 | 21-1 v Coggeshall TownCoggeshall Town 1-1 Witham Town |
| 27 | Sat 12 Mar 2022 | 20-1 v Felixstowe & Walton UnitedWitham Town 0-1 Felixstowe & Walton United |
| 28 | Sat 19 Mar 2022 | 33-2 v Grays AthleticGrays Athletic 2-3 Witham Town |
| 29 | Sat 26 Mar 2022 | 32-3 v Brentwood TownBrentwood Town 3-2 Witham Town |
| 30 | Sat 2 Apr 2022 | 31-5 v AveleyWitham Town 1-5 Aveley |
| 31 | Sat 9 Apr 2022 | 51-2 v Stowmarket TownWitham Town 1-2 Stowmarket Town |
| 32 | Sat 16 Apr 2022 | 52-3 v AFC SudburyAFC Sudbury 3-2 Witham Town |
| 33 | Mon 18 Apr 2022 | 32-2 v Heybridge SwiftsWitham Town 2-2 Heybridge Swifts |
| 34 | Sat 23 Apr 2022 | 33-2 v RomfordRomford 2-3 Witham Town |
| 35 | Sat 30 Apr 2022 | 3 3-0 v Saffron Walden TownWitham Town 3-0 Saffron Walden Town |
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