| 1 | Sun 25 Aug 2019 | 471-2 v TorinoTorino 2-1 Sassuolo |
| 2 | Sun 1 Sep 2019 | 474-1 v SampdoriaSassuolo 4-1 Sampdoria |
| 3 | Sun 22 Sep 2019 | 473-0 v SPALSassuolo 3-0 SPAL |
| 4 | Wed 25 Sep 2019 | 470-1 v ParmaParma 1-0 Sassuolo |
| 5 | Sat 28 Sep 2019 | 471-4 v AtalantaSassuolo 1-4 Atalanta |
| 6 | Sun 20 Oct 2019 | 473-4 v Inter MilanSassuolo 3-4 Inter Milan |
| 7 | Fri 25 Oct 2019 | 471-0 v Hellas VeronaHellas Verona 0-1 Sassuolo |
| 8 | Sun 3 Nov 2019 | 472-2 v LecceLecce 2-2 Sassuolo |
| 9 | Fri 8 Nov 2019 | 473-1 v BolognaSassuolo 3-1 Bologna |
| 10 | Sun 24 Nov 2019 | 471-2 v LazioSassuolo 1-2 Lazio |
| 11 | Sun 5 Jan 2020 | 471-2 v GenoaGenoa 2-1 Sassuolo |
| 12 | Sun 12 Jan 2020 | 470-3 v UdineseUdinese 3-0 Sassuolo |
| 13 | Sat 18 Jan 2020 | 472-1 v TorinoSassuolo 2-1 Torino |
| 14 | Sun 26 Jan 2020 | 470-0 v SampdoriaSampdoria 0-0 Sassuolo |
| 15 | Sat 1 Feb 2020 | 474-2 v RomaSassuolo 4-2 Roma |
| 16 | Sun 9 Feb 2020 | 47 2-1 v SPALSPAL 1-2 Sassuolo |
| 17 | Sun 16 Feb 2020 | 470-1 v ParmaSassuolo 0-1 Parma |
| 18 | Mon 9 Mar 2020 | 473-0 v BresciaSassuolo 3-0 Brescia |
| 19 | Wed 24 Jun 2020 | 473-3 v Inter MilanInter Milan 3-3 Sassuolo |
| 20 | Sun 28 Jun 2020 | 473-3 v Hellas VeronaSassuolo 3-3 Hellas Verona |
| 21 | Sat 4 Jul 2020 | 474-2 v LecceSassuolo 4-2 Lecce |
| 22 | Wed 8 Jul 2020 | 472-1 v BolognaBologna 1-2 Sassuolo |
| 23 | Sat 11 Jul 2020 | 472-1 v LazioLazio 1-2 Sassuolo |
| 24 | Wed 15 Jul 2020 | 473-3 v JuventusSassuolo 3-3 Juventus |
| 25 | Tue 21 Jul 2020 | 471-2 v AC MilanSassuolo 1-2 AC Milan |
| 26 | Sat 25 Jul 2020 | 470-2 v NapoliNapoli 2-0 Sassuolo |
| 27 | Wed 29 Jul 2020 | 475-0 v GenoaSassuolo 5-0 Genoa |
| 28 | Sun 2 Aug 2020 | 470-1 v UdineseSassuolo 0-1 Udinese |
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