| 1 | Sun 18 Oct 2020 | 982-2 v SpeziaSpezia 2-2 Fiorentina |
| 2 | Sat 7 Nov 2020 | 980-0 v ParmaParma 0-0 Fiorentina |
| 3 | Sun 22 Nov 2020 | 980-1 v BeneventoFiorentina 0-1 Benevento |
| 4 | Wed 16 Dec 2020 | 981-1 v SassuoloFiorentina 1-1 Sassuolo |
| 5 | Sat 19 Dec 2020 | 98 1-1 v Hellas VeronaFiorentina 1-1 Hellas Verona |
| 6 | Tue 22 Dec 2020 | 983-0 v JuventusJuventus 0-3 Fiorentina |
| 7 | Sun 3 Jan 2021 | 98 0-0 v BolognaFiorentina 0-0 Bologna |
| 8 | Wed 6 Jan 2021 | 981-2 v LazioLazio 2-1 Fiorentina |
| 9 | Sun 10 Jan 2021 | 981-0 v CagliariFiorentina 1-0 Cagliari |
| 10 | Sun 17 Jan 2021 | 980-6 v NapoliNapoli 6-0 Fiorentina |
| 11 | Sat 23 Jan 2021 | 98 2-1 v CrotoneFiorentina 2-1 Crotone |
| 12 | Fri 29 Jan 2021 | 981-1 v TorinoTorino 1-1 Fiorentina |
| 13 | Fri 5 Feb 2021 | 980-2 v Inter MilanFiorentina 0-2 Inter Milan |
| 14 | Fri 19 Feb 2021 | 983-0 v SpeziaFiorentina 3-0 Spezia |
| 15 | Wed 3 Mar 2021 | 981-2 v RomaFiorentina 1-2 Roma |
| 16 | Tue 20 Apr 2021 | 982-1 v Hellas VeronaHellas Verona 1-2 Fiorentina |
| 17 | Sun 25 Apr 2021 | 98 1-1 v JuventusFiorentina 1-1 Juventus |
| 18 | Sun 2 May 2021 | 98 3-3 v BolognaBologna 3-3 Fiorentina |
| 19 | Wed 12 May 2021 | 980-0 v CagliariCagliari 0-0 Fiorentina |
| 20 | Sun 16 May 2021 | 980-2 v NapoliFiorentina 0-2 Napoli |
| 21 | Sat 22 May 2021 | 980-0 v CrotoneCrotone 0-0 Fiorentina |
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