| 1 | Sat 19 Sep 2020 | 231-0 v TorinoFiorentina 1-0 Torino |
| 2 | Sun 25 Oct 2020 | 233-2 v UdineseFiorentina 3-2 Udinese |
| 3 | Sat 7 Nov 2020 | 230-0 v ParmaParma 0-0 Fiorentina |
| 4 | Sun 13 Dec 2020 | 230-3 v AtalantaAtalanta 3-0 Fiorentina |
| 5 | Wed 16 Dec 2020 | 231-1 v SassuoloFiorentina 1-1 Sassuolo |
| 6 | Sat 19 Dec 2020 | 231-1 v Hellas VeronaFiorentina 1-1 Hellas Verona |
| 7 | Tue 22 Dec 2020 | 233-0 v JuventusJuventus 0-3 Fiorentina |
| 8 | Sun 3 Jan 2021 | 230-0 v BolognaFiorentina 0-0 Bologna |
| 9 | Wed 6 Jan 2021 | 231-2 v LazioLazio 2-1 Fiorentina |
| 10 | Sun 10 Jan 2021 | 231-0 v CagliariFiorentina 1-0 Cagliari |
| 11 | Sun 17 Jan 2021 | 230-6 v NapoliNapoli 6-0 Fiorentina |
| 12 | Fri 29 Jan 2021 | 231-1 v TorinoTorino 1-1 Fiorentina |
| 13 | Fri 5 Feb 2021 | 230-2 v Inter MilanFiorentina 0-2 Inter Milan |
| 14 | Sun 14 Feb 2021 | 23 1-2 v SampdoriaSampdoria 2-1 Fiorentina |
| 15 | Fri 19 Feb 2021 | 233-0 v SpeziaFiorentina 3-0 Spezia |
| 16 | Wed 3 Mar 2021 | 231-2 v RomaFiorentina 1-2 Roma |
| 17 | Sat 13 Mar 2021 | 234-1 v BeneventoBenevento 1-4 Fiorentina |
| 18 | Sun 21 Mar 2021 | 232-3 v AC MilanFiorentina 2-3 AC Milan |
| 19 | Sat 3 Apr 2021 | 231-1 v GenoaGenoa 1-1 Fiorentina |
| 20 | Sun 11 Apr 2021 | 232-3 v AtalantaFiorentina 2-3 Atalanta |
| 21 | Sat 17 Apr 2021 | 231-3 v SassuoloSassuolo 3-1 Fiorentina |
| 22 | Tue 20 Apr 2021 | 232-1 v Hellas VeronaHellas Verona 1-2 Fiorentina |
| 23 | Sun 25 Apr 2021 | 231-1 v JuventusFiorentina 1-1 Juventus |
| 24 | Sun 2 May 2021 | 233-3 v BolognaBologna 3-3 Fiorentina |
| 25 | Sat 8 May 2021 | 23 2-0 v LazioFiorentina 2-0 Lazio |
| 26 | Wed 12 May 2021 | 230-0 v CagliariCagliari 0-0 Fiorentina |
| 27 | Sun 16 May 2021 | 230-2 v NapoliFiorentina 0-2 Napoli |
| 28 | Sat 22 May 2021 | 230-0 v CrotoneCrotone 0-0 Fiorentina |
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