| 1 | Sat 3 Oct 2020 | 160-1 v RomaUdinese 0-1 Roma |
| 2 | Sun 25 Oct 2020 | 162-3 v FiorentinaFiorentina 3-2 Udinese |
| 3 | Sun 29 Nov 2020 | 163-1 v LazioLazio 1-3 Udinese |
| 4 | Tue 15 Dec 2020 | 160-0 v CrotoneUdinese 0-0 Crotone |
| 5 | Sun 3 Jan 2021 | 161-4 v JuventusJuventus 4-1 Udinese |
| 6 | Wed 6 Jan 2021 | 162-2 v BolognaBologna 2-2 Udinese |
| 7 | Sun 10 Jan 2021 | 161-2 v NapoliUdinese 1-2 Napoli |
| 8 | Sat 16 Jan 2021 | 161-2 v SampdoriaSampdoria 2-1 Udinese |
| 9 | Wed 20 Jan 2021 | 161-1 v AtalantaUdinese 1-1 Atalanta |
| 10 | Sat 23 Jan 2021 | 160-0 v Inter MilanUdinese 0-0 Inter Milan |
| 11 | Sun 31 Jan 2021 | 161-0 v SpeziaSpezia 0-1 Udinese |
| 12 | Sun 7 Feb 2021 | 162-0 v Hellas VeronaUdinese 2-0 Hellas Verona |
| 13 | Sun 14 Feb 2021 | 160-3 v RomaRoma 3-0 Udinese |
| 14 | Sun 21 Feb 2021 | 162-2 v ParmaParma 2-2 Udinese |
| 15 | Sun 28 Feb 2021 | 161-0 v FiorentinaUdinese 1-0 Fiorentina |
| 16 | Wed 3 Mar 2021 | 161-1 v AC MilanAC Milan 1-1 Udinese |
| 17 | Sat 6 Mar 2021 | 162-0 v SassuoloUdinese 2-0 Sassuolo |
| 18 | Sat 13 Mar 2021 | 161-1 v GenoaGenoa 1-1 Udinese |
| 19 | Sun 21 Mar 2021 | 16 0-1 v LazioUdinese 0-1 Lazio |
| 20 | Sat 3 Apr 2021 | 162-3 v AtalantaAtalanta 3-2 Udinese |
| 21 | Sat 10 Apr 2021 | 160-1 v TorinoUdinese 0-1 Torino |
| 22 | Sat 17 Apr 2021 | 162-1 v CrotoneCrotone 1-2 Udinese |
| 23 | Wed 21 Apr 2021 | 160-1 v CagliariUdinese 0-1 Cagliari |
| 24 | Sun 25 Apr 2021 | 164-2 v BeneventoBenevento 2-4 Udinese |
| 25 | Sun 2 May 2021 | 161-2 v JuventusUdinese 1-2 Juventus |
| 26 | Sat 8 May 2021 | 161-1 v BolognaUdinese 1-1 Bologna |
| 27 | Tue 11 May 2021 | 161-5 v NapoliNapoli 5-1 Udinese |
| 28 | Sun 16 May 2021 | 160-1 v SampdoriaUdinese 0-1 Sampdoria |
| 29 | Sun 23 May 2021 | 161-5 v Inter MilanInter Milan 5-1 Udinese |
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