| 1 | Sat 19 Aug | 36 1-3 v NapoliFrosinone 1-3 Napoli |
| 2 | Sat 26 Aug | 362-1 v AtalantaFrosinone 2-1 Atalanta |
| 3 | Sat 2 Sep | 360-0 v UdineseUdinese 0-0 Frosinone |
| 4 | Sun 17 Sep | 364-2 v SassuoloFrosinone 4-2 Sassuolo |
| 5 | Fri 22 Sep | 361-1 v SalernitanaSalernitana 1-1 Frosinone |
| 6 | Thu 28 Sep | 36 1-1 v FiorentinaFrosinone 1-1 Fiorentina |
| 7 | Sun 1 Oct | 360-2 v RomaRoma 2-0 Frosinone |
| 8 | Sun 8 Oct | 362-1 v Hellas VeronaFrosinone 2-1 Hellas Verona |
| 9 | Sun 22 Oct | 36 1-2 v BolognaBologna 2-1 Frosinone |
| 10 | Mon 6 Nov | 362-1 v EmpoliFrosinone 2-1 Empoli |
| 11 | Sun 12 Nov | 360-2 v Inter MilanInter Milan 2-0 Frosinone |
| 12 | Sat 6 Jan | 362-3 v MonzaFrosinone 2-3 Monza |
| 13 | Mon 15 Jan | 360-5 v AtalantaAtalanta 5-0 Frosinone |
| 14 | Sun 21 Jan | 363-1 v CagliariFrosinone 3-1 Cagliari |
| 15 | Sun 28 Jan | 36 1-1 v Hellas VeronaHellas Verona 1-1 Frosinone |
| 16 | Sat 3 Feb | 362-3 v AC MilanFrosinone 2-3 AC Milan |
| 17 | Sun 11 Feb | 361-5 v FiorentinaFiorentina 5-1 Frosinone |
| 18 | Sun 18 Feb | 360-3 v RomaFrosinone 0-3 Roma |
| 19 | Sun 25 Feb | 362-3 v JuventusJuventus 3-2 Frosinone |
| 20 | Sun 3 Mar | 361-1 v LecceFrosinone 1-1 Lecce |
| 21 | Sat 9 Mar | 360-1 v SassuoloSassuolo 1-0 Frosinone |
| 22 | Sat 16 Mar | 362-3 v LazioFrosinone 2-3 Lazio |
| 23 | Sat 30 Mar | 361-1 v GenoaGenoa 1-1 Frosinone |
| 24 | Sun 7 Apr | 360-0 v BolognaFrosinone 0-0 Bologna |
| 25 | Sun 14 Apr | 362-2 v NapoliNapoli 2-2 Frosinone |
| 26 | Sun 21 Apr | 360-0 v TorinoTorino 0-0 Frosinone |
| 27 | Fri 26 Apr | 36 3-0 v SalernitanaFrosinone 3-0 Salernitana |
| 28 | Sun 5 May | 360-0 v EmpoliEmpoli 0-0 Frosinone |
| 29 | Fri 10 May | 360-5 v Inter MilanFrosinone 0-5 Inter Milan |
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