| 1 | Sat 19 Sep 2020 | 3 1-0 v Crewe AlexandraHull City 1-0 Crewe Alexandra |
| 2 | Sat 26 Sep 2020 | 32-0 v Northampton TownNorthampton Town 0-2 Hull City |
| 3 | Sat 3 Oct 2020 | 31-0 v Plymouth ArgyleHull City 1-0 Plymouth Argyle |
| 4 | Fri 9 Oct 2020 | 31-4 v Fleetwood TownFleetwood Town 4-1 Hull City |
| 5 | Sat 17 Oct 2020 | 33-0 v RochdaleRochdale 0-3 Hull City |
| 6 | Tue 20 Oct 2020 | 31-0 v AFC WimbledonHull City 1-0 AFC Wimbledon |
| 7 | Sat 24 Oct 2020 | 3 1-2 v Peterborough UnitedHull City 1-2 Peterborough United |
| 8 | Tue 27 Oct 2020 | 3 3-1 v Bristol RoversBristol Rovers 1-3 Hull City |
| 9 | Sat 31 Oct 2020 | 3 1-2 v Swindon TownSwindon Town 2-1 Hull City |
| 10 | Sat 14 Nov 2020 | 32-0 v Burton AlbionHull City 2-0 Burton Albion |
| 11 | Sat 21 Nov 2020 | 33-1 v Milton Keynes DonsMilton Keynes Dons 1-3 Hull City |
| 12 | Tue 24 Nov 2020 | 33-0 v Ipswich TownIpswich Town 0-3 Hull City |
| 13 | Wed 2 Dec 2020 | 32-1 v Doncaster RoversHull City 2-1 Doncaster Rovers |
| 14 | Sat 5 Dec 2020 | 31-1 v Oxford UnitedOxford United 1-1 Hull City |
| 15 | Sat 12 Dec 2020 | 30-1 v Shrewsbury TownHull City 0-1 Shrewsbury Town |
| 16 | Tue 15 Dec 2020 | 32-3 v BlackpoolBlackpool 3-2 Hull City |
| 17 | Fri 18 Dec 2020 | 30-2 v PortsmouthHull City 0-2 Portsmouth |
| 18 | Sat 9 Jan 2021 | 31-1 v SunderlandSunderland 1-1 Hull City |
| 19 | Sat 16 Jan 2021 | 31-1 v BlackpoolHull City 1-1 Blackpool |
| 20 | Tue 19 Jan 2021 | 33-0 v Accrington StanleyHull City 3-0 Accrington Stanley |
| 21 | Sat 23 Jan 2021 | 34-0 v PortsmouthPortsmouth 0-4 Hull City |
| 22 | Tue 26 Jan 2021 | 3 0-2 v Accrington StanleyAccrington Stanley 2-0 Hull City |
| 23 | Sat 30 Jan 2021 | 31-0 v Swindon TownHull City 1-0 Swindon Town |
| 24 | Sat 6 Feb 2021 | 30-1 v Burton AlbionBurton Albion 1-0 Hull City |
| 25 | Tue 9 Feb 2021 | 30-0 v Lincoln CityHull City 0-0 Lincoln City |
| 26 | Sat 13 Feb 2021 | 30-1 v Milton Keynes DonsHull City 0-1 Milton Keynes Dons |
| 27 | Wed 17 Feb 2021 | 35-0 v Wigan AthleticWigan Athletic 0-5 Hull City |
| 28 | Sat 20 Feb 2021 | 33-3 v Doncaster RoversDoncaster Rovers 3-3 Hull City |
| 29 | Tue 23 Feb 2021 | 3 0-1 v Ipswich TownHull City 0-1 Ipswich Town |
| 30 | Sat 27 Feb 2021 | 33-0 v AFC WimbledonAFC Wimbledon 0-3 Hull City |
| 31 | Tue 2 Mar 2021 | 32-0 v RochdaleHull City 2-0 Rochdale |
| 32 | Sat 6 Mar 2021 | 32-0 v Bristol RoversHull City 2-0 Bristol Rovers |
| 33 | Tue 9 Mar 2021 | 33-1 v Peterborough UnitedPeterborough United 1-3 Hull City |
| 34 | Sat 13 Mar 2021 | 32-0 v Oxford UnitedHull City 2-0 Oxford United |
| 35 | Sat 20 Mar 2021 | 31-1 v Shrewsbury TownShrewsbury Town 1-1 Hull City |
| 36 | Sat 27 Mar 2021 | 31-1 v GillinghamHull City 1-1 Gillingham |
| 37 | Fri 2 Apr 2021 | 32-1 v Crewe AlexandraCrewe Alexandra 1-2 Hull City |
| 38 | Mon 5 Apr 2021 | 33-0 v Northampton TownHull City 3-0 Northampton Town |
| 39 | Sat 10 Apr 2021 | 33-0 v Plymouth ArgylePlymouth Argyle 0-3 Hull City |
| 40 | Sat 17 Apr 2021 | 32-1 v Fleetwood TownHull City 2-1 Fleetwood Town |
| 41 | Tue 20 Apr 2021 | 32-2 v SunderlandHull City 2-2 Sunderland |
| 42 | Sat 24 Apr 2021 | 32-1 v Lincoln CityLincoln City 1-2 Hull City |
| 43 | Sat 1 May 2021 | 33-1 v Wigan AthleticHull City 3-1 Wigan Athletic |
| 44 | Sun 9 May 2021 | 30-1 v Charlton AthleticCharlton Athletic 1-0 Hull City |
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