| 1 | Sat 17 Aug | 42-0 v Ipswich TownIpswich Town 0-2 Liverpool | Premier League |
| 2 | Sun 25 Aug | 42-0 v BrentfordLiverpool 2-0 Brentford | Premier League |
| 3 | Sun 1 Sep | 4 3-0 v Manchester UnitedManchester United 0-3 Liverpool | Premier League |
| 4 | Sat 14 Sep | 40-1 v Nottingham ForestLiverpool 0-1 Nottingham Forest | Premier League |
| 5 | Tue 17 Sep | 43-1 v AC MilanAC Milan 1-3 Liverpool | UEFA Champions League Matchday 1 |
| 6 | Sat 21 Sep | 43-0 v AFC BournemouthLiverpool 3-0 AFC Bournemouth | Premier League |
| 7 | Sat 28 Sep | 42-1 v Wolverhampton WanderersWolverhampton Wanderers 1-2 Liverpool | Premier League |
| 8 | Wed 2 Oct | 4 2-0 v BolognaLiverpool 2-0 Bologna | UEFA Champions League Matchday 2 |
| 9 | Sat 5 Oct | 41-0 v Crystal PalaceCrystal Palace 0-1 Liverpool | Premier League |
| 10 | Sun 20 Oct | 42-1 v ChelseaLiverpool 2-1 Chelsea | Premier League |
| 11 | Wed 23 Oct | 41-0 v RB LeipzigRB Leipzig 0-1 Liverpool | UEFA Champions League Matchday 3 |
| 12 | Sun 27 Oct | 42-2 v ArsenalArsenal 2-2 Liverpool | Premier League |
| 13 | Sat 2 Nov | 42-1 v Brighton & Hove AlbionLiverpool 2-1 Brighton & Hove Albion | Premier League |
| 14 | Tue 5 Nov | 44-0 v Bayer 04 LeverkusenLiverpool 4-0 Bayer 04 Leverkusen | UEFA Champions League Matchday 4 |
| 15 | Sat 9 Nov | 42-0 v Aston VillaLiverpool 2-0 Aston Villa | Premier League |
| 16 | Sun 24 Nov | 43-2 v SouthamptonSouthampton 2-3 Liverpool | Premier League |
| 17 | Wed 27 Nov | 42-0 v Real MadridLiverpool 2-0 Real Madrid | UEFA Champions League Matchday 5 |
| 18 | Sun 1 Dec | 42-0 v Manchester CityLiverpool 2-0 Manchester City | Premier League |
| 19 | Wed 4 Dec | 43-3 v Newcastle UnitedNewcastle United 3-3 Liverpool | Premier League |
| 20 | Tue 10 Dec | 41-0 v GironaGirona 0-1 Liverpool | UEFA Champions League Matchday 6 |
| 21 | Sat 14 Dec | 42-2 v FulhamLiverpool 2-2 Fulham | Premier League |
| 22 | Sun 22 Dec | 46-3 v Tottenham HotspurTottenham Hotspur 3-6 Liverpool | Premier League |
| 23 | Thu 26 Dec | 43-1 v Leicester CityLiverpool 3-1 Leicester City | Premier League |
| 24 | Sun 29 Dec | 45-0 v West Ham UnitedWest Ham United 0-5 Liverpool | Premier League |
| 25 | Sun 5 Jan | 42-2 v Manchester UnitedLiverpool 2-2 Manchester United | Premier League |
| 26 | Wed 8 Jan | 40-1 v Tottenham HotspurTottenham Hotspur 1-0 Liverpool | Carabao Cup Semi Final |
| 27 | Tue 14 Jan | 41-1 v Nottingham ForestNottingham Forest 1-1 Liverpool | Premier League |
| 28 | Sat 18 Jan | 42-0 v BrentfordBrentford 0-2 Liverpool | Premier League |
| 29 | Tue 21 Jan | 42-1 v LilleLiverpool 2-1 Lille | UEFA Champions League Matchday 7 |
| 30 | Sat 25 Jan | 44-1 v Ipswich TownLiverpool 4-1 Ipswich Town | Premier League |
| 31 | Sat 1 Feb | 4 2-0 v AFC BournemouthAFC Bournemouth 0-2 Liverpool | Premier League |
| 32 | Thu 6 Feb | 44-0 v Tottenham HotspurLiverpool 4-0 Tottenham Hotspur | Carabao Cup Semi Final |
| 33 | Wed 12 Feb | 42-2 v EvertonEverton 2-2 Liverpool | Premier League |
| 34 | Sun 16 Feb | 4 2-1 v Wolverhampton WanderersLiverpool 2-1 Wolverhampton Wanderers | Premier League |
| 35 | Wed 19 Feb | 42-2 v Aston VillaAston Villa 2-2 Liverpool | Premier League |
| 36 | Sun 23 Feb | 42-0 v Manchester CityManchester City 0-2 Liverpool | Premier League |
| 37 | Wed 26 Feb | 42-0 v Newcastle UnitedLiverpool 2-0 Newcastle United | Premier League |
| 38 | Wed 5 Mar | 4 1-0 v Paris St GermainParis St Germain 0-1 Liverpool | UEFA Champions League Round of 16 |
| 39 | Sat 8 Mar | 43-1 v SouthamptonLiverpool 3-1 Southampton | Premier League |
| 40 | Tue 11 Mar | 40-1 v Paris St GermainLiverpool 0-1 Paris St Germain | UEFA Champions League Round of 16 |
| 41 | Sun 16 Mar | 41-2 v Newcastle UnitedLiverpool 1-2 Newcastle United | Carabao Cup Final |
| 42 | Wed 2 Apr | 41-0 v EvertonLiverpool 1-0 Everton | Premier League |
| 43 | Sun 6 Apr | 42-3 v FulhamFulham 3-2 Liverpool | Premier League |
| 44 | Sun 13 Apr | 42-1 v West Ham UnitedLiverpool 2-1 West Ham United | Premier League |
| 45 | Sun 20 Apr | 41-0 v Leicester CityLeicester City 0-1 Liverpool | Premier League |
| 46 | Sun 27 Apr | 45-1 v Tottenham HotspurLiverpool 5-1 Tottenham Hotspur | Premier League |
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