| 1 | Sat 31 Aug | 143-3 v VfB StuttgartVfB Stuttgart 3-3 Mainz 05 | German Bundesliga |
| 2 | Sun 15 Sep | 141-2 v Werder BremenMainz 05 1-2 Werder Bremen | German Bundesliga |
| 3 | Fri 20 Sep | 143-2 v FC AugsburgFC Augsburg 2-3 Mainz 05 | German Bundesliga |
| 4 | Sat 28 Sep | 140-2 v 1 FC HeidenheimMainz 05 0-2 1 FC Heidenheim | German Bundesliga |
| 5 | Sat 5 Oct | 143-0 v FC St PauliFC St Pauli 0-3 Mainz 05 | German Bundesliga |
| 6 | Fri 25 Oct | 141-1 v Borussia MönchengladbachMainz 05 1-1 Borussia Mönchengladbach | German Bundesliga |
| 7 | Sun 3 Nov | 140-0 v SC FreiburgSC Freiburg 0-0 Mainz 05 | German Bundesliga |
| 8 | Sat 9 Nov | 143-1 v Borussia DortmundMainz 05 3-1 Borussia Dortmund | German Bundesliga |
| 9 | Sun 24 Nov | 143-0 v Holstein KielHolstein Kiel 0-3 Mainz 05 | German Bundesliga |
| 10 | Sun 1 Dec | 142-0 v 1899 HoffenheimMainz 05 2-0 1899 Hoffenheim | German Bundesliga |
| 11 | Sun 8 Dec | 143-4 v VfL WolfsburgVfL Wolfsburg 4-3 Mainz 05 | German Bundesliga |
| 12 | Sat 14 Dec | 142-1 v Bayern MunichMainz 05 2-1 Bayern Munich | German Bundesliga |
| 13 | Sat 21 Dec | 143-1 v Eintracht FrankfurtEintracht Frankfurt 1-3 Mainz 05 | German Bundesliga |
| 14 | Sat 11 Jan | 142-0 v VfL BochumMainz 05 2-0 VfL Bochum | German Bundesliga |
| 15 | Tue 14 Jan | 140-1 v Bayer 04 LeverkusenBayer 04 Leverkusen 1-0 Mainz 05 | German Bundesliga |
| 16 | Fri 31 Jan | 140-1 v Werder BremenWerder Bremen 1-0 Mainz 05 | German Bundesliga |
| 17 | Sun 30 Mar | 141-3 v Borussia DortmundBorussia Dortmund 3-1 Mainz 05 | German Bundesliga |
| 18 | Sat 5 Apr | 141-1 v Holstein KielMainz 05 1-1 Holstein Kiel | German Bundesliga |
| 19 | Sat 12 Apr | 140-2 v 1899 Hoffenheim1899 Hoffenheim 2-0 Mainz 05 | German Bundesliga |
| 20 | Sat 19 Apr | 142-2 v VfL WolfsburgMainz 05 2-2 VfL Wolfsburg | German Bundesliga |
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