| 1 | 20/9/2020 | 271-3 v RB LeipzigRB Leipzig 3-1 Mainz 05 | German Bundesliga |
| 2 | 26/9/2020 | 271-4 v VfB StuttgartMainz 05 1-4 VfB Stuttgart | German Bundesliga |
| 3 | 2/10/2020 | 270-4 v 1. FC Union Berlin1. FC Union Berlin 4-0 Mainz 05 | German Bundesliga |
| 4 | 17/10/2020 | 270-1 v Bayer 04 LeverkusenMainz 05 0-1 Bayer 04 Leverkusen | German Bundesliga |
| 5 | 24/10/2020 | 27 2-3 v Borussia MönchengladbachMainz 05 2-3 Borussia Mönchengladbach | German Bundesliga |
| 6 | 31/10/2020 | 271-3 v FC AugsburgFC Augsburg 3-1 Mainz 05 | German Bundesliga |
| 7 | 7/11/2020 | 272-2 v FC Schalke 04Mainz 05 2-2 FC Schalke 04 | German Bundesliga |
| 8 | 22/11/2020 | 273-1 v SC FreiburgSC Freiburg 1-3 Mainz 05 | German Bundesliga |
| 9 | 29/11/2020 | 271-1 v 1899 HoffenheimMainz 05 1-1 1899 Hoffenheim | German Bundesliga |
| 10 | 5/12/2020 | 271-2 v Arminia BielefeldArminia Bielefeld 2-1 Mainz 05 | German Bundesliga |
| 11 | 12/12/2020 | 270-1 v 1. FC KölnMainz 05 0-1 1. FC Köln | German Bundesliga |
| 12 | 15/12/2020 | 270-0 v Hertha BerlinHertha Berlin 0-0 Mainz 05 | German Bundesliga |
| 13 | 19/12/2020 | 270-1 v Werder BremenMainz 05 0-1 Werder Bremen | German Bundesliga |
| 14 | 9/1/2021 | 270-2 v Eintracht FrankfurtMainz 05 0-2 Eintracht Frankfurt | German Bundesliga |
| 15 | 16/1/2021 | 271-1 v Borussia DortmundBorussia Dortmund 1-1 Mainz 05 | German Bundesliga |
| 16 | 19/1/2021 | 270-2 v VfL WolfsburgMainz 05 0-2 VfL Wolfsburg | German Bundesliga |
| 17 | 23/1/2021 | 273-2 v RB LeipzigMainz 05 3-2 RB Leipzig | German Bundesliga |
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