| 1 | Sun 26 Nov | 301-1 v 1899 Hoffenheim1899 Hoffenheim 1-1 Mainz 05 | German Bundesliga |
| 2 | Sun 3 Dec | 300-1 v SC FreiburgMainz 05 0-1 SC Freiburg | German Bundesliga |
| 3 | Sun 10 Dec | 30 0-0 v 1 FC Köln1 FC Köln 0-0 Mainz 05 | German Bundesliga |
| 4 | Tue 19 Dec | 301-1 v Borussia DortmundBorussia Dortmund 1-1 Mainz 05 | German Bundesliga |
| 5 | Sat 13 Jan | 30 1-1 v VfL WolfsburgMainz 05 1-1 VfL Wolfsburg | German Bundesliga |
| 6 | Fri 26 Jan | 30 0-1 v Eintracht FrankfurtEintracht Frankfurt 1-0 Mainz 05 | German Bundesliga |
| 7 | Sat 3 Feb | 300-1 v Werder BremenMainz 05 0-1 Werder Bremen | German Bundesliga |
| 8 | Wed 7 Feb | 301-1 v 1 FC Union BerlinMainz 05 1-1 1 FC Union Berlin | German Bundesliga |
| 9 | Fri 23 Feb | 301-2 v Bayer 04 LeverkusenBayer 04 Leverkusen 2-1 Mainz 05 | German Bundesliga |
| 10 | Sat 2 Mar | 301-1 v Borussia MönchengladbachMainz 05 1-1 Borussia Mönchengladbach | German Bundesliga |
| 11 | Sat 9 Mar | 30 1-8 v Bayern MunichBayern Munich 8-1 Mainz 05 | German Bundesliga |
| 12 | Sat 16 Mar | 302-0 v VfL BochumMainz 05 2-0 VfL Bochum | German Bundesliga |
| 13 | Sat 30 Mar | 300-0 v RB LeipzigRB Leipzig 0-0 Mainz 05 | German Bundesliga |
| 14 | Sat 6 Apr | 304-0 v Darmstadt 98Mainz 05 4-0 Darmstadt 98 | German Bundesliga |
| 15 | Sat 13 Apr | 304-1 v 1899 HoffenheimMainz 05 4-1 1899 Hoffenheim | German Bundesliga |
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