| 1 | Thu 21 Sep | 380-1 v RangersRangers 1-0 Real Betis | UEFA Europa League Group C |
| 2 | Thu 28 Sep | 381-1 v GranadaGranada 1-1 Real Betis | Spanish La Liga |
| 3 | Sun 1 Oct | 383-0 v ValenciaReal Betis 3-0 Valencia | Spanish La Liga |
| 4 | Thu 5 Oct | 38 2-1 v Sparta PragueReal Betis 2-1 Sparta Prague | UEFA Europa League Group C |
| 5 | Sun 8 Oct | 381-1 v AlavésAlavés 1-1 Real Betis | Spanish La Liga |
| 6 | Sat 21 Oct | 381-1 v GetafeGetafe 1-1 Real Betis | Spanish La Liga |
| 7 | Thu 26 Oct | 381-0 v Aris LimassolAris Limassol 0-1 Real Betis | UEFA Europa League Group C |
| 8 | Sun 29 Oct | 38 2-1 v OsasunaReal Betis 2-1 Osasuna | Spanish La Liga |
| 9 | Sat 4 Nov | 382-0 v MallorcaReal Betis 2-0 Mallorca | Spanish La Liga |
| 10 | Sun 12 Nov | 381-1 v SevillaSevilla 1-1 Real Betis | Spanish La Liga |
| 11 | Thu 30 Nov | 380-1 v Sparta PragueSparta Prague 1-0 Real Betis | UEFA Europa League Group C |
| 12 | Sun 3 Dec | 38 0-0 v AlmeríaAlmería 0-0 Real Betis | Spanish La Liga |
| 13 | Sat 9 Dec | 381-1 v Real MadridReal Betis 1-1 Real Madrid | Spanish La Liga |
| 14 | Thu 14 Dec | 382-3 v RangersReal Betis 2-3 Rangers | UEFA Europa League Group C |
| 15 | Sun 17 Dec | 380-0 v Real SociedadReal Sociedad 0-0 Real Betis | Spanish La Liga |
| 16 | Thu 21 Dec | 381-1 v GironaReal Betis 1-1 Girona | Spanish La Liga |
| 17 | Wed 3 Jan | 381-2 v Celta VigoCelta Vigo 2-1 Real Betis | Spanish La Liga |
| 18 | Sat 13 Jan | 38 1-0 v GranadaReal Betis 1-0 Granada | Spanish La Liga |
| 19 | Sun 21 Jan | 382-4 v BarcelonaReal Betis 2-4 Barcelona | Spanish La Liga |
| 20 | Sat 27 Jan | 381-0 v MallorcaMallorca 0-1 Real Betis | Spanish La Liga |
| 21 | Sun 4 Feb | 38 1-1 v GetafeReal Betis 1-1 Getafe | Spanish La Liga |
| 22 | Thu 15 Feb | 38 0-1 v Dinamo ZagrebReal Betis 0-1 Dinamo Zagreb | UEFA Europa Conference League |
| 23 | Thu 22 Feb | 381-1 v Dinamo ZagrebDinamo Zagreb 1-1 Real Betis | UEFA Europa Conference League |
| 24 | Sun 25 Feb | 383-1 v Athletic BilbaoReal Betis 3-1 Athletic Bilbao | Spanish La Liga |
| 25 | Sun 17 Mar | 380-2 v Rayo VallecanoRayo Vallecano 2-0 Real Betis | Spanish La Liga |
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