| 1 | Sun 15 Oct | 45-0 v Bristol CityManchester City 5-0 Bristol City | FA Women's Super League |
| 2 | Sat 21 Oct | 41-0 v Leicester CityLeicester City 0-1 Manchester City | FA Women's Super League |
| 3 | Sun 5 Nov | 41-2 v ArsenalArsenal 2-1 Manchester City | FA Women's Super League |
| 4 | Sun 12 Nov | 40-1 v Brighton & Hove AlbionManchester City 0-1 Brighton & Hove Albion | FA Women's Super League |
| 5 | Sun 19 Nov | 4 3-1 v Manchester UnitedManchester United 1-3 Manchester City | FA Women's Super League |
| 6 | Sun 26 Nov | 47-0 v Tottenham HotspurManchester City 7-0 Tottenham Hotspur | FA Women's Super League |
| 7 | Sat 9 Dec | 42-1 v Aston VillaManchester City 2-1 Aston Villa | FA Women's Super League |
| 8 | Sun 17 Dec | 44-1 v EvertonEverton 1-4 Manchester City | FA Women's Super League |
| 9 | Sun 21 Jan | 45-1 v LiverpoolManchester City 5-1 Liverpool | FA Women's Super League |
| 10 | Sun 28 Jan | 42-0 v Tottenham HotspurTottenham Hotspur 0-2 Manchester City | FA Women's Super League |
| 11 | Sun 4 Feb | 42-0 v Leicester CityManchester City 2-0 Leicester City | FA Women's Super League |
| 12 | Fri 16 Feb | 41-0 v ChelseaChelsea 0-1 Manchester City | FA Women's Super League |
| 13 | Sat 2 Mar | 42-1 v EvertonManchester City 2-1 Everton | FA Women's Super League |
| 14 | Sun 17 Mar | 44-1 v Brighton & Hove AlbionBrighton & Hove Albion 1-4 Manchester City | FA Women's Super League |
| 15 | Sat 23 Mar | 43-1 v Manchester UnitedManchester City 3-1 Manchester United | FA Women's Super League |
| 16 | Sat 30 Mar | 44-1 v LiverpoolLiverpool 1-4 Manchester City | FA Women's Super League |
| 17 | Sun 21 Apr | 45-0 v West Ham UnitedManchester City 5-0 West Ham United | FA Women's Super League |
| 18 | Sun 28 Apr | 44-0 v Bristol CityBristol City 0-4 Manchester City | FA Women's Super League |
| 19 | Sun 5 May | 41-2 v ArsenalManchester City 1-2 Arsenal | FA Women's Super League |
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