| 1 | 3/10/2020 | 31-1 v Leeds UnitedLeeds United 1-1 Manchester City | Premier League |
| 2 | 17/10/2020 | 3 1-0 v ArsenalManchester City 1-0 Arsenal | Premier League |
| 3 | 21/10/2020 | 33-1 v FC PortoManchester City 3-1 FC Porto | UEFA Champions League Group C |
| 4 | 24/10/2020 | 31-1 v West Ham UnitedWest Ham United 1-1 Manchester City | Premier League |
| 5 | 27/10/2020 | 33-0 v MarseilleMarseille 0-3 Manchester City | UEFA Champions League Group C |
| 6 | 31/10/2020 | 31-0 v Sheffield UnitedSheffield United 0-1 Manchester City | Premier League |
| 7 | 3/11/2020 | 33-0 v OlympiakosManchester City 3-0 Olympiakos | UEFA Champions League Group C |
| 8 | 8/11/2020 | 31-1 v LiverpoolManchester City 1-1 Liverpool | Premier League |
| 9 | 21/11/2020 | 3 0-2 v Tottenham HotspurTottenham Hotspur 2-0 Manchester City | Premier League |
| 10 | 25/11/2020 | 3 1-0 v OlympiakosOlympiakos 0-1 Manchester City | UEFA Champions League Group C |
| 11 | 28/11/2020 | 35-0 v BurnleyManchester City 5-0 Burnley | Premier League |
| 12 | 1/12/2020 | 30-0 v FC PortoFC Porto 0-0 Manchester City | UEFA Champions League Group C |
| 13 | 5/12/2020 | 32-0 v FulhamManchester City 2-0 Fulham | Premier League |
| 14 | 12/12/2020 | 30-0 v Manchester UnitedManchester United 0-0 Manchester City | Premier League |
| 15 | 15/12/2020 | 31-1 v West Bromwich AlbionManchester City 1-1 West Bromwich Albion | Premier League |
| 16 | 19/12/2020 | 31-0 v SouthamptonSouthampton 0-1 Manchester City | Premier League |
| 17 | 22/12/2020 | 34-1 v ArsenalArsenal 1-4 Manchester City | Carabao Cup Quarter Final |
| 18 | 26/12/2020 | 32-0 v Newcastle UnitedManchester City 2-0 Newcastle United | Premier League |
| 19 | 3/1/2021 | 33-1 v ChelseaChelsea 1-3 Manchester City | Premier League |
| 20 | 6/1/2021 | 32-0 v Manchester UnitedManchester United 0-2 Manchester City | Carabao Cup Semi Final |
| 21 | 10/1/2021 | 33-0 v Birmingham CityManchester City 3-0 Birmingham City | Emirates FA Cup Third Round |
| 22 | 13/1/2021 | 31-0 v Brighton & Hove AlbionManchester City 1-0 Brighton & Hove Albion | Premier League |
| 23 | 17/1/2021 | 34-0 v Crystal PalaceManchester City 4-0 Crystal Palace | Premier League |
| 24 | 20/1/2021 | 32-0 v Aston VillaManchester City 2-0 Aston Villa | Premier League |
| 25 | 23/1/2021 | 33-1 v Cheltenham TownCheltenham Town 1-3 Manchester City | Emirates FA Cup Fourth Round |
| 26 | 26/1/2021 | 35-0 v West Bromwich AlbionWest Bromwich Albion 0-5 Manchester City | Premier League |
| 27 | 30/1/2021 | 31-0 v Sheffield UnitedManchester City 1-0 Sheffield United | Premier League |
| 28 | 3/2/2021 | 32-0 v BurnleyBurnley 0-2 Manchester City | Premier League |
| 29 | 7/2/2021 | 3 4-1 v LiverpoolLiverpool 1-4 Manchester City | Premier League |
| 30 | 13/2/2021 | 33-0 v Tottenham HotspurManchester City 3-0 Tottenham Hotspur | Premier League |
| 31 | 17/2/2021 | 33-1 v EvertonEverton 1-3 Manchester City | Premier League |
| 32 | 21/2/2021 | 31-0 v ArsenalArsenal 0-1 Manchester City | Premier League |
| 33 | 24/2/2021 | 32-0 v Borussia MönchengladbachBorussia Mönchengladbach 0-2 Manchester City | UEFA Champions League Round of 16 |
| 34 | 27/2/2021 | 32-1 v West Ham UnitedManchester City 2-1 West Ham United | Premier League |
| 35 | 2/3/2021 | 34-1 v Wolverhampton WanderersManchester City 4-1 Wolverhampton Wanderers | Premier League |
| 36 | 7/3/2021 | 30-2 v Manchester UnitedManchester City 0-2 Manchester United | Premier League |
| 37 | 10/3/2021 | 35-2 v SouthamptonManchester City 5-2 Southampton | Premier League |
| 38 | 13/3/2021 | 33-0 v FulhamFulham 0-3 Manchester City | Premier League |
| 39 | 16/3/2021 | 32-0 v Borussia MönchengladbachManchester City 2-0 Borussia Mönchengladbach | UEFA Champions League Round of 16 |
| 40 | 20/3/2021 | 32-0 v EvertonEverton 0-2 Manchester City | Emirates FA Cup Sixth Round |
| 41 | 3/4/2021 | 32-0 v Leicester CityLeicester City 0-2 Manchester City | Premier League |
| 42 | 6/4/2021 | 32-1 v Borussia DortmundManchester City 2-1 Borussia Dortmund | UEFA Champions League Quarter Final |
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