| 1 | Sat 10 Aug | 81-1 v Manchester CityManchester City 1-1 Manchester United | Community Shield Final |
| 2 | Fri 16 Aug | 81-0 v FulhamManchester United 1-0 Fulham | Premier League |
| 3 | Sat 24 Aug | 81-2 v Brighton & Hove AlbionBrighton & Hove Albion 2-1 Manchester United | Premier League |
| 4 | Sun 1 Sep | 80-3 v LiverpoolManchester United 0-3 Liverpool | Premier League |
| 5 | Sat 14 Sep | 8 3-0 v SouthamptonSouthampton 0-3 Manchester United | Premier League |
| 6 | Tue 17 Sep | 87-0 v BarnsleyManchester United 7-0 Barnsley | Carabao Cup Third Round |
| 7 | Sat 21 Sep | 80-0 v Crystal PalaceCrystal Palace 0-0 Manchester United | Premier League |
| 8 | Wed 25 Sep | 81-1 v FC TwenteManchester United 1-1 FC Twente | UEFA Europa League Matchday 1 |
| 9 | Sun 29 Sep | 8 0-3 v Tottenham HotspurManchester United 0-3 Tottenham Hotspur | Premier League |
| 10 | Thu 3 Oct | 8 3-3 v FC PortoFC Porto 3-3 Manchester United | UEFA Europa League Matchday 2 |
| 11 | Sun 6 Oct | 80-0 v Aston VillaAston Villa 0-0 Manchester United | Premier League |
| 12 | Sat 19 Oct | 82-1 v BrentfordManchester United 2-1 Brentford | Premier League |
| 13 | Sun 27 Oct | 81-2 v West Ham UnitedWest Ham United 2-1 Manchester United | Premier League |
| 14 | Wed 30 Oct | 85-2 v Leicester CityManchester United 5-2 Leicester City | Carabao Cup Round of 16 |
| 15 | Sun 3 Nov | 81-1 v ChelseaManchester United 1-1 Chelsea | Premier League |
| 16 | Thu 7 Nov | 82-0 v PAOK FCManchester United 2-0 PAOK FC | UEFA Europa League Matchday 4 |
| 17 | Sun 10 Nov | 83-0 v Leicester CityManchester United 3-0 Leicester City | Premier League |
| 18 | Sun 24 Nov | 81-1 v Ipswich TownIpswich Town 1-1 Manchester United | Premier League |
| 19 | Thu 28 Nov | 83-2 v FK Bodø/GlimtManchester United 3-2 FK Bodø/Glimt | UEFA Europa League Matchday 5 |
| 20 | Sun 1 Dec | 84-0 v EvertonManchester United 4-0 Everton | Premier League |
| 21 | Wed 4 Dec | 80-2 v ArsenalArsenal 2-0 Manchester United | Premier League |
| 22 | Sat 7 Dec | 82-3 v Nottingham ForestManchester United 2-3 Nottingham Forest | Premier League |
| 23 | Thu 12 Dec | 82-1 v Viktoria PlzenViktoria Plzen 1-2 Manchester United | UEFA Europa League Matchday 6 |
| 24 | Sun 15 Dec | 82-1 v Manchester CityManchester City 1-2 Manchester United | Premier League |
| 25 | Thu 19 Dec | 8 3-4 v Tottenham HotspurTottenham Hotspur 4-3 Manchester United | Carabao Cup Quarter Final |
| 26 | Sun 22 Dec | 80-3 v AFC BournemouthManchester United 0-3 AFC Bournemouth | Premier League |
| 27 | Thu 26 Dec | 8 0-2 v Wolverhampton WanderersWolverhampton Wanderers 2-0 Manchester United | Premier League |
| 28 | Sun 5 Jan | 82-2 v LiverpoolLiverpool 2-2 Manchester United | Premier League |
| 29 | Sun 12 Jan | 8 1-1 v ArsenalArsenal 1-1 Manchester United | Emirates FA Cup Third Round |
| 30 | Thu 16 Jan | 83-1 v SouthamptonManchester United 3-1 Southampton | Premier League |
| 31 | Sun 19 Jan | 81-3 v Brighton & Hove AlbionManchester United 1-3 Brighton & Hove Albion | Premier League |
| 32 | Thu 23 Jan | 82-1 v RangersManchester United 2-1 Rangers | UEFA Europa League Matchday 7 |
| 33 | Sun 26 Jan | 81-0 v FulhamFulham 0-1 Manchester United | Premier League |
| 34 | Thu 30 Jan | 82-0 v Steaua BucharestSteaua Bucharest 0-2 Manchester United | UEFA Europa League Matchday 8 |
| 35 | Sun 2 Feb | 8 0-2 v Crystal PalaceManchester United 0-2 Crystal Palace | Premier League |
| 36 | Fri 7 Feb | 82-1 v Leicester CityManchester United 2-1 Leicester City | Emirates FA Cup Fourth Round |
| 37 | Sun 16 Feb | 80-1 v Tottenham HotspurTottenham Hotspur 1-0 Manchester United | Premier League |
| 38 | Sat 22 Feb | 82-2 v EvertonEverton 2-2 Manchester United | Premier League |
| 39 | Wed 26 Feb | 83-2 v Ipswich TownManchester United 3-2 Ipswich Town | Premier League |
| 40 | Sun 2 Mar | 81-1 v FulhamManchester United 1-1 Fulham | Emirates FA Cup Fifth Round |
| 41 | Thu 6 Mar | 8 1-1 v Real SociedadReal Sociedad 1-1 Manchester United | UEFA Europa League Round of 16 |
| 42 | Sun 9 Mar | 81-1 v ArsenalManchester United 1-1 Arsenal | Premier League |
| 43 | Thu 13 Mar | 84-1 v Real SociedadManchester United 4-1 Real Sociedad | UEFA Europa League Round of 16 |
| 44 | Sun 16 Mar | 83-0 v Leicester CityLeicester City 0-3 Manchester United | Premier League |
| 45 | Tue 1 Apr | 80-1 v Nottingham ForestNottingham Forest 1-0 Manchester United | Premier League |
| 46 | Sun 6 Apr | 80-0 v Manchester CityManchester United 0-0 Manchester City | Premier League |
| 47 | Thu 10 Apr | 82-2 v LyonLyon 2-2 Manchester United | UEFA Europa League Quarter Final |
| 48 | Sun 13 Apr | 81-4 v Newcastle UnitedNewcastle United 4-1 Manchester United | Premier League |
| 49 | Thu 17 Apr | 85-4 v LyonManchester United 5-4 Lyon | UEFA Europa League Quarter Final |
| 50 | Sun 20 Apr | 80-1 v Wolverhampton WanderersManchester United 0-1 Wolverhampton Wanderers | Premier League |
| 51 | Sun 27 Apr | 81-1 v AFC BournemouthAFC Bournemouth 1-1 Manchester United | Premier League |
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