| 1 | Sat 10 Aug | 61-1 v Manchester CityManchester City 1-1 Manchester United | Community Shield Final |
| 2 | Fri 16 Aug | 61-0 v FulhamManchester United 1-0 Fulham | Premier League |
| 3 | Sat 24 Aug | 61-2 v Brighton & Hove AlbionBrighton & Hove Albion 2-1 Manchester United | Premier League |
| 4 | Sun 1 Sep | 6 0-3 v LiverpoolManchester United 0-3 Liverpool | Premier League |
| 5 | Sat 14 Sep | 63-0 v SouthamptonSouthampton 0-3 Manchester United | Premier League |
| 6 | Sat 21 Sep | 6 0-0 v Crystal PalaceCrystal Palace 0-0 Manchester United | Premier League |
| 7 | Wed 25 Sep | 6 1-1 v FC TwenteManchester United 1-1 FC Twente | UEFA Europa League Matchday 1 |
| 8 | Sun 29 Sep | 6 0-3 v Tottenham HotspurManchester United 0-3 Tottenham Hotspur | Premier League |
| 9 | Thu 3 Oct | 63-3 v FC PortoFC Porto 3-3 Manchester United | UEFA Europa League Matchday 2 |
| 10 | Sat 19 Oct | 62-1 v BrentfordManchester United 2-1 Brentford | Premier League |
| 11 | Thu 24 Oct | 61-1 v FenerbahçeFenerbahçe 1-1 Manchester United | UEFA Europa League Matchday 3 |
| 12 | Sun 27 Oct | 61-2 v West Ham UnitedWest Ham United 2-1 Manchester United | Premier League |
| 13 | Wed 30 Oct | 65-2 v Leicester CityManchester United 5-2 Leicester City | Carabao Cup Round of 16 |
| 14 | Sun 3 Nov | 6 1-1 v ChelseaManchester United 1-1 Chelsea | Premier League |
| 15 | Thu 7 Nov | 62-0 v PAOK FCManchester United 2-0 PAOK FC | UEFA Europa League Matchday 4 |
| 16 | Sun 10 Nov | 63-0 v Leicester CityManchester United 3-0 Leicester City | Premier League |
| 17 | Thu 28 Nov | 63-2 v FK Bodø/GlimtManchester United 3-2 FK Bodø/Glimt | UEFA Europa League Matchday 5 |
| 18 | Sun 1 Dec | 6 4-0 v EvertonManchester United 4-0 Everton | Premier League |
| 19 | Sat 7 Dec | 62-3 v Nottingham ForestManchester United 2-3 Nottingham Forest | Premier League |
| 20 | Thu 12 Dec | 62-1 v Viktoria PlzenViktoria Plzen 1-2 Manchester United | UEFA Europa League Matchday 6 |
| 21 | Sun 15 Dec | 62-1 v Manchester CityManchester City 1-2 Manchester United | Premier League |
| 22 | Thu 19 Dec | 63-4 v Tottenham HotspurTottenham Hotspur 4-3 Manchester United | Carabao Cup Quarter Final |
| 23 | Sun 22 Dec | 60-3 v AFC BournemouthManchester United 0-3 AFC Bournemouth | Premier League |
| 24 | Thu 26 Dec | 60-2 v Wolverhampton WanderersWolverhampton Wanderers 2-0 Manchester United | Premier League |
| 25 | Mon 30 Dec | 6 0-2 v Newcastle UnitedManchester United 0-2 Newcastle United | Premier League |
| 26 | Sun 5 Jan | 62-2 v LiverpoolLiverpool 2-2 Manchester United | Premier League |
| 27 | Sun 12 Jan | 6 1-1 v ArsenalArsenal 1-1 Manchester United | Emirates FA Cup Third Round |
| 28 | Thu 16 Jan | 6 3-1 v SouthamptonManchester United 3-1 Southampton | Premier League |
| 29 | Thu 23 Jan | 62-1 v RangersManchester United 2-1 Rangers | UEFA Europa League Matchday 7 |
| 30 | Sun 26 Jan | 61-0 v FulhamFulham 0-1 Manchester United | Premier League |
| 31 | Thu 30 Jan | 62-0 v Steaua BucharestSteaua Bucharest 0-2 Manchester United | UEFA Europa League Matchday 8 |
| 32 | Sun 2 Feb | 60-2 v Crystal PalaceManchester United 0-2 Crystal Palace | Premier League |
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