| 1 | Mon 14 Aug | 391-0 v Wolverhampton WanderersManchester United 1-0 Wolverhampton Wanderers | Premier League |
| 2 | Sat 26 Aug | 393-2 v Nottingham ForestManchester United 3-2 Nottingham Forest | Premier League |
| 3 | Sat 16 Sep | 391-3 v Brighton & Hove AlbionManchester United 1-3 Brighton & Hove Albion | Premier League |
| 4 | Wed 20 Sep | 393-4 v Bayern MunichBayern Munich 4-3 Manchester United | UEFA Champions League Group A |
| 5 | Sat 23 Sep | 391-0 v BurnleyBurnley 0-1 Manchester United | Premier League |
| 6 | Sat 7 Oct | 392-1 v BrentfordManchester United 2-1 Brentford | Premier League |
| 7 | Sat 21 Oct | 392-1 v Sheffield UnitedSheffield United 1-2 Manchester United | Premier League |
| 8 | Tue 24 Oct | 39 1-0 v FC CopenhagenManchester United 1-0 FC Copenhagen | UEFA Champions League Group A |
| 9 | Sun 29 Oct | 390-3 v Manchester CityManchester United 0-3 Manchester City | Premier League |
| 10 | Sat 4 Nov | 391-0 v FulhamFulham 0-1 Manchester United | Premier League |
| 11 | Wed 8 Nov | 393-4 v FC CopenhagenFC Copenhagen 4-3 Manchester United | UEFA Champions League Group A |
| 12 | Sat 11 Nov | 391-0 v Luton TownManchester United 1-0 Luton Town | Premier League |
| 13 | Sun 26 Nov | 393-0 v EvertonEverton 0-3 Manchester United | Premier League |
| 14 | Wed 29 Nov | 393-3 v GalatasarayGalatasaray 3-3 Manchester United | UEFA Champions League Group A |
| 15 | Sat 2 Dec | 390-1 v Newcastle UnitedNewcastle United 1-0 Manchester United | Premier League |
| 16 | Wed 6 Dec | 392-1 v ChelseaManchester United 2-1 Chelsea | Premier League |
| 17 | Sat 9 Dec | 390-3 v AFC BournemouthManchester United 0-3 AFC Bournemouth | Premier League |
| 18 | Tue 12 Dec | 390-1 v Bayern MunichManchester United 0-1 Bayern Munich | UEFA Champions League Group A |
| 19 | Sun 17 Dec | 390-0 v LiverpoolLiverpool 0-0 Manchester United | Premier League |
| 20 | Sat 23 Dec | 390-2 v West Ham UnitedWest Ham United 2-0 Manchester United | Premier League |
| 21 | Tue 26 Dec | 393-2 v Aston VillaManchester United 3-2 Aston Villa | Premier League |
| 22 | Sat 30 Dec | 391-2 v Nottingham ForestNottingham Forest 2-1 Manchester United | Premier League |
| 23 | Mon 8 Jan | 392-0 v Wigan AthleticWigan Athletic 0-2 Manchester United | Emirates FA Cup Third Round |
| 24 | Sun 14 Jan | 392-2 v Tottenham HotspurManchester United 2-2 Tottenham Hotspur | Premier League |
| 25 | Sun 28 Jan | 394-2 v Newport CountyNewport County 2-4 Manchester United | Emirates FA Cup Fourth Round |
| 26 | Thu 1 Feb | 394-3 v Wolverhampton WanderersWolverhampton Wanderers 3-4 Manchester United | Premier League |
| 27 | Sun 4 Feb | 393-0 v West Ham UnitedManchester United 3-0 West Ham United | Premier League |
| 28 | Sun 11 Feb | 392-1 v Aston VillaAston Villa 1-2 Manchester United | Premier League |
| 29 | Sun 18 Feb | 392-1 v Luton TownLuton Town 1-2 Manchester United | Premier League |
| 30 | Sat 24 Feb | 391-2 v FulhamManchester United 1-2 Fulham | Premier League |
| 31 | Wed 28 Feb | 391-0 v Nottingham ForestNottingham Forest 0-1 Manchester United | Emirates FA Cup Fifth Round |
| 32 | Sun 3 Mar | 391-3 v Manchester CityManchester City 3-1 Manchester United | Premier League |
| 33 | Sat 9 Mar | 39 2-0 v EvertonManchester United 2-0 Everton | Premier League |
| 34 | Sun 17 Mar | 394-3 v LiverpoolManchester United 4-3 Liverpool | Emirates FA Cup Quarter Final |
| 35 | Sat 30 Mar | 39 1-1 v BrentfordBrentford 1-1 Manchester United | Premier League |
| 36 | Thu 4 Apr | 393-4 v ChelseaChelsea 4-3 Manchester United | Premier League |
| 37 | Sun 21 Apr | 393-3 v Coventry CityCoventry City 3-3 Manchester United | Emirates FA Cup Semi Final |
| 38 | Wed 24 Apr | 394-2 v Sheffield UnitedManchester United 4-2 Sheffield United | Premier League |
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