| 1 | Mon 31 Jul | 32-0 v AvroAvro 0-2 Guiseley | Friendly |
| 2 | Sat 12 Aug | 31-1 v Hyde UnitedHyde United 1-1 Guiseley | Northern Premier League - Premier Division |
| 3 | Tue 15 Aug | 31-3 v Whitby TownGuiseley 1-3 Whitby Town | Northern Premier League - Premier Division |
| 4 | Sat 19 Aug | 32-1 v Basford UnitedGuiseley 2-1 Basford United | Northern Premier League - Premier Division |
| 5 | Tue 22 Aug | 3 0-4 v Gainsborough TrinityGainsborough Trinity 4-0 Guiseley | Northern Premier League - Premier Division |
| 6 | Sat 26 Aug | 32-2 v Lancaster CityLancaster City 2-2 Guiseley | Northern Premier League - Premier Division |
| 7 | Mon 28 Aug | 32-2 v Bradford (Park Avenue)Guiseley 2-2 Bradford (Park Avenue) | Northern Premier League - Premier Division |
| 8 | Sat 23 Sep | 60-1 v Ashton UnitedGuiseley 0-1 Ashton United | Northern Premier League - Premier Division |
| 9 | Tue 26 Sep | 31-1 v Morpeth TownMorpeth Town 1-1 Guiseley | Northern Premier League - Premier Division |
| 10 | Tue 3 Oct | 310-1 v Ilkley TownGuiseley 10-1 Ilkley Town | The West Riding County Cup First Round |
| 11 | Sat 7 Oct | 33-1 v Gainsborough TrinityGainsborough Trinity 1-3 Guiseley | Isuzu FA Trophy Third Qualifying Round |
| 12 | Tue 10 Oct | 33-2 v Atherton CollieriesGuiseley 3-2 Atherton Collieries | Northern Premier League - Premier Division |
| 13 | Sat 14 Oct | 52-0 v Stafford RangersGuiseley 2-0 Stafford Rangers | Northern Premier League - Premier Division |
| 14 | Tue 24 Oct | 34-2 v MarineGuiseley 4-2 Marine | Northern Premier League - Premier Division |
| 15 | Sat 28 Oct | 31-1 v Walsall WoodWalsall Wood 1-1 Guiseley | Isuzu FA Trophy First Round |
| 16 | Tue 31 Oct | 3 1-1 v Worksop TownWorksop Town 1-1 Guiseley | Northern Premier League - Premier Division |
| 17 | Sat 4 Nov | 31-0 v Warrington RylandsWarrington Rylands 0-1 Guiseley | Northern Premier League - Premier Division |
| 18 | Sat 11 Nov | 3 4-3 v Workington AFCGuiseley 4-3 Workington AFC | Northern Premier League - Premier Division |
| 19 | Sat 18 Nov | 62-3 v FC United of ManchesterFC United of Manchester 3-2 Guiseley | Northern Premier League - Premier Division |
| 20 | Tue 21 Nov | 64-0 v Matlock TownGuiseley 4-0 Matlock Town | Northern Premier League - Premier Division |
| 21 | Sat 25 Nov | 3 1-5 v MacclesfieldMacclesfield 5-1 Guiseley | Northern Premier League - Premier Division |
| 22 | Tue 28 Nov | 3 4-1 v Ilkeston TownIlkeston Town 1-4 Guiseley | Northern Premier League - Premier Division |
| 23 | Sat 16 Dec | 32-2 v Hyde UnitedGuiseley 2-2 Hyde United | Northern Premier League - Premier Division |
| 24 | Sat 23 Dec | 31-0 v Basford UnitedBasford United 0-1 Guiseley | Northern Premier League - Premier Division |
| 25 | Mon 1 Jan | 31-0 v Bradford (Park Avenue)Bradford (Park Avenue) 0-1 Guiseley | Northern Premier League - Premier Division |
| 26 | Sat 6 Jan | 30-1 v Gainsborough TrinityGuiseley 0-1 Gainsborough Trinity | Northern Premier League - Premier Division |
| 27 | Sat 13 Jan | 212-0 v Bamber BridgeGuiseley 2-0 Bamber Bridge | Northern Premier League - Premier Division |
| 28 | Sat 27 Jan | 31-2 v MacclesfieldGuiseley 1-2 Macclesfield | Northern Premier League - Premier Division |
| 29 | Sat 3 Feb | 34-3 v RadcliffeRadcliffe 3-4 Guiseley | Northern Premier League - Premier Division |
| 30 | Tue 6 Feb | 31-1 v Ossett UnitedGuiseley 1-1 Ossett United | The West Riding County Cup Quarter Final |
| 31 | Sat 10 Feb | 31-1 v Ashton UnitedAshton United 1-1 Guiseley | Northern Premier League - Premier Division |
| 32 | Sat 17 Feb | 3 4-1 v Morpeth TownGuiseley 4-1 Morpeth Town | Northern Premier League - Premier Division |
| 33 | Sat 24 Feb | 31-2 v Stafford RangersStafford Rangers 2-1 Guiseley | Northern Premier League - Premier Division |
| 34 | Tue 5 Mar | 32-1 v Atherton CollieriesAtherton Collieries 1-2 Guiseley | Northern Premier League - Premier Division |
| 35 | Sat 9 Mar | 31-0 v RadcliffeGuiseley 1-0 Radcliffe | Northern Premier League - Premier Division |
| 36 | Wed 27 Mar | 31-2 v Knaresborough TownKnaresborough Town 2-1 Guiseley | The West Riding County Cup Semi Final |
| 37 | Sat 30 Mar | 32-3 v Lancaster CityGuiseley 2-3 Lancaster City | Northern Premier League - Premier Division |
| 38 | Sat 6 Apr | 30-2 v Warrington RylandsGuiseley 0-2 Warrington Rylands | Northern Premier League - Premier Division |
| 39 | Sat 13 Apr | 3 1-2 v Matlock TownMatlock Town 2-1 Guiseley | Northern Premier League - Premier Division |
| 40 | Sat 20 Apr | 33-1 v FC United of ManchesterGuiseley 3-1 FC United of Manchester | Northern Premier League - Premier Division |
| 41 | Tue 23 Apr | 3 2-4 v Worksop TownGuiseley 2-4 Worksop Town | Northern Premier League - Premier Division |
| 42 | Sat 27 Apr | 31-2 v Workington AFCWorkington AFC 2-1 Guiseley | Northern Premier League - Premier Division |
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