| 1 | Sat 5 Aug 2017 | 4 2-2 v Lincoln CityWycombe Wanderers 2-2 Lincoln City | Sky Bet League Two |
| 2 | Sat 12 Aug 2017 | 43-2 v Port ValePort Vale 2-3 Wycombe Wanderers | Sky Bet League Two |
| 3 | Sat 19 Aug 2017 | 4 2-4 v Notts CountyWycombe Wanderers 2-4 Notts County | Sky Bet League Two |
| 4 | Sat 26 Aug 2017 | 43-2 v Grimsby TownGrimsby Town 2-3 Wycombe Wanderers | Sky Bet League Two |
| 5 | Tue 29 Aug 2017 | 41-5 v Bristol RoversWycombe Wanderers 1-5 Bristol Rovers | Checkatrade Trophy Southern Group C |
| 6 | Sat 2 Sep 2017 | 43-1 v Forest Green RoversWycombe Wanderers 3-1 Forest Green Rovers | Sky Bet League Two |
| 7 | Sat 9 Sep 2017 | 4 0-0 v Newport CountyNewport County 0-0 Wycombe Wanderers | Sky Bet League Two |
| 8 | Tue 12 Sep 2017 | 4 0-0 v Mansfield TownMansfield Town 0-0 Wycombe Wanderers | Sky Bet League Two |
| 9 | Sat 16 Sep 2017 | 41-2 v Luton TownWycombe Wanderers 1-2 Luton Town | Sky Bet League Two |
| 10 | Sat 30 Sep 2017 | 43-1 v BarnetWycombe Wanderers 3-1 Barnet | Sky Bet League Two |
| 11 | Sat 14 Oct 2017 | 40-0 v Exeter CityWycombe Wanderers 0-0 Exeter City | Sky Bet League Two |
| 12 | Tue 17 Oct 2017 | 43-3 v Carlisle UnitedCarlisle United 3-3 Wycombe Wanderers | Sky Bet League Two |
| 13 | Sat 21 Oct 2017 | 40-1 v Swindon TownSwindon Town 1-0 Wycombe Wanderers | Sky Bet League Two |
| 14 | Sat 28 Oct 2017 | 43-3 v Cheltenham TownWycombe Wanderers 3-3 Cheltenham Town | Sky Bet League Two |
| 15 | Tue 31 Oct 2017 | 40-1 v Swindon TownSwindon Town 1-0 Wycombe Wanderers | Checkatrade Trophy Southern Group C |
| 16 | Sun 5 Nov 2017 | 42-0 v Solihull MoorsSolihull Moors 0-2 Wycombe Wanderers | Emirates FA Cup First Round |
| 17 | Sat 11 Nov 2017 | 41-2 v MorecambeMorecambe 2-1 Wycombe Wanderers | Sky Bet League Two |
| 18 | Sat 18 Nov 2017 | 44-0 v Crawley TownWycombe Wanderers 4-0 Crawley Town | Sky Bet League Two |
| 19 | Tue 26 Dec 2017 | 42-0 v Newport CountyWycombe Wanderers 2-0 Newport County | Sky Bet League Two |
| 20 | Sat 30 Dec 2017 | 41-2 v Mansfield TownWycombe Wanderers 1-2 Mansfield Town | Sky Bet League Two |
| 21 | Mon 1 Jan 2018 | 42-1 v Forest Green RoversForest Green Rovers 1-2 Wycombe Wanderers | Sky Bet League Two |
| 22 | Sat 20 Jan 2018 | 43-2 v Crewe AlexandraCrewe Alexandra 2-3 Wycombe Wanderers | Sky Bet League Two |
| 23 | Tue 30 Jan 2018 | 43-2 v Luton TownLuton Town 2-3 Wycombe Wanderers | Sky Bet League Two |
| 24 | Sat 3 Feb 2018 | 44-3 v Carlisle UnitedWycombe Wanderers 4-3 Carlisle United | Sky Bet League Two |
| 25 | Sat 10 Feb 2018 | 41-1 v Exeter CityExeter City 1-1 Wycombe Wanderers | Sky Bet League Two |
| 26 | Tue 13 Feb 2018 | 43-2 v Swindon TownWycombe Wanderers 3-2 Swindon Town | Sky Bet League Two |
| 27 | Sat 17 Feb 2018 | 42-0 v Cheltenham TownCheltenham Town 0-2 Wycombe Wanderers | Sky Bet League Two |
| 28 | Sat 24 Feb 2018 | 42-4 v MorecambeWycombe Wanderers 2-4 Morecambe | Sky Bet League Two |
| 29 | Tue 27 Feb 2018 | 40-1 v Coventry CityWycombe Wanderers 0-1 Coventry City | Sky Bet League Two |
| 30 | Sat 10 Mar 2018 | 41-1 v Cambridge UnitedWycombe Wanderers 1-1 Cambridge United | Sky Bet League Two |
| 31 | Sat 17 Mar 2018 | 42-0 v BarnetBarnet 0-2 Wycombe Wanderers | Sky Bet League Two |
| 32 | Wed 21 Mar 2018 | 43-2 v Crawley TownCrawley Town 2-3 Wycombe Wanderers | Sky Bet League Two |
| 33 | Sat 24 Mar 2018 | 40-0 v Port ValeWycombe Wanderers 0-0 Port Vale | Sky Bet League Two |
| 34 | Mon 2 Apr 2018 | 42-1 v Grimsby TownWycombe Wanderers 2-1 Grimsby Town | Sky Bet League Two |
| 35 | Sat 14 Apr 2018 | 41-0 v Yeovil TownYeovil Town 0-1 Wycombe Wanderers | Sky Bet League Two |
| 36 | Sat 21 Apr 2018 | 40-4 v Accrington StanleyWycombe Wanderers 0-4 Accrington Stanley | Sky Bet League Two |
| 37 | Sat 28 Apr 2018 | 42-1 v ChesterfieldChesterfield 1-2 Wycombe Wanderers | Sky Bet League Two |
| 38 | Sat 5 May 2018 | 41-0 v StevenageWycombe Wanderers 1-0 Stevenage | Sky Bet League Two |
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