| 1 | Fri 4 Aug 2017 | 50-3 v Manchester CityManchester City 3-0 West Ham United | Friendly |
| 2 | Sun 13 Aug 2017 | 5 0-4 v Manchester UnitedManchester United 4-0 West Ham United | Premier League |
| 3 | Sat 19 Aug 2017 | 52-3 v SouthamptonSouthampton 3-2 West Ham United | Premier League |
| 4 | Sat 26 Aug 2017 | 50-3 v Newcastle UnitedNewcastle United 3-0 West Ham United | Premier League |
| 5 | Mon 11 Sep 2017 | 5 2-0 v Huddersfield TownWest Ham United 2-0 Huddersfield Town | Premier League |
| 6 | Sat 16 Sep 2017 | 5 0-0 v West Bromwich AlbionWest Bromwich Albion 0-0 West Ham United | Premier League |
| 7 | Sat 23 Sep 2017 | 52-3 v Tottenham HotspurWest Ham United 2-3 Tottenham Hotspur | Premier League |
| 8 | Sat 30 Sep 2017 | 51-0 v Swansea CityWest Ham United 1-0 Swansea City | Premier League |
| 9 | Sat 14 Oct 2017 | 51-1 v BurnleyBurnley 1-1 West Ham United | Premier League |
| 10 | Fri 20 Oct 2017 | 50-3 v Brighton & Hove AlbionWest Ham United 0-3 Brighton & Hove Albion | Premier League |
| 11 | Sat 28 Oct 2017 | 5 2-2 v Crystal PalaceCrystal Palace 2-2 West Ham United | Premier League |
| 12 | Sun 19 Nov 2017 | 50-2 v WatfordWatford 2-0 West Ham United | Premier League |
| 13 | Fri 24 Nov 2017 | 51-1 v Leicester CityWest Ham United 1-1 Leicester City | Premier League |
| 14 | Wed 29 Nov 2017 | 5 0-4 v EvertonEverton 4-0 West Ham United | Premier League |
| 15 | Sun 3 Dec 2017 | 51-2 v Manchester CityManchester City 2-1 West Ham United | Premier League |
| 16 | Sat 9 Dec 2017 | 51-0 v ChelseaWest Ham United 1-0 Chelsea | Premier League |
| 17 | Wed 13 Dec 2017 | 50-0 v ArsenalWest Ham United 0-0 Arsenal | Premier League |
| 18 | Sat 16 Dec 2017 | 53-0 v Stoke CityStoke City 0-3 West Ham United | Premier League |
| 19 | Sat 23 Dec 2017 | 52-3 v Newcastle UnitedWest Ham United 2-3 Newcastle United | Premier League |
| 20 | Tue 26 Dec 2017 | 5 3-3 v AFC BournemouthAFC Bournemouth 3-3 West Ham United | Premier League |
| 21 | Tue 2 Jan 2018 | 52-1 v West Bromwich AlbionWest Ham United 2-1 West Bromwich Albion | Premier League |
| 22 | Thu 4 Jan 2018 | 51-1 v Tottenham HotspurTottenham Hotspur 1-1 West Ham United | Premier League |
| 23 | Sat 13 Jan 2018 | 54-1 v Huddersfield TownHuddersfield Town 1-4 West Ham United | Premier League |
| 24 | Tue 16 Jan 2018 | 51-0 v Shrewsbury TownWest Ham United 1-0 Shrewsbury Town | Emirates FA Cup Third Round |
| 25 | Sat 20 Jan 2018 | 51-1 v AFC BournemouthWest Ham United 1-1 AFC Bournemouth | Premier League |
| 26 | Sat 27 Jan 2018 | 50-2 v Wigan AthleticWigan Athletic 2-0 West Ham United | Emirates FA Cup Fourth Round |
| 27 | Tue 30 Jan 2018 | 51-1 v Crystal PalaceWest Ham United 1-1 Crystal Palace | Premier League |
| 28 | Sat 3 Feb 2018 | 51-3 v Brighton & Hove AlbionBrighton & Hove Albion 3-1 West Ham United | Premier League |
| 29 | Sat 10 Feb 2018 | 5 2-0 v WatfordWest Ham United 2-0 Watford | Premier League |
| 30 | Sat 24 Feb 2018 | 51-4 v LiverpoolLiverpool 4-1 West Ham United | Premier League |
| 31 | Sat 3 Mar 2018 | 51-4 v Swansea CitySwansea City 4-1 West Ham United | Premier League |
| 32 | Sat 10 Mar 2018 | 50-3 v BurnleyWest Ham United 0-3 Burnley | Premier League |
| 33 | Sat 31 Mar 2018 | 53-0 v SouthamptonWest Ham United 3-0 Southampton | Premier League |
| 34 | Sun 8 Apr 2018 | 51-1 v ChelseaChelsea 1-1 West Ham United | Premier League |
| 35 | Mon 16 Apr 2018 | 51-1 v Stoke CityWest Ham United 1-1 Stoke City | Premier League |
| 36 | Sun 22 Apr 2018 | 5 1-4 v ArsenalArsenal 4-1 West Ham United | Premier League |
| 37 | Sun 29 Apr 2018 | 51-4 v Manchester CityWest Ham United 1-4 Manchester City | Premier League |
| 38 | Sat 5 May 2018 | 52-0 v Leicester CityLeicester City 0-2 West Ham United | Premier League |
| 39 | Thu 10 May 2018 | 50-0 v Manchester UnitedWest Ham United 0-0 Manchester United | Premier League |
| 40 | Sun 13 May 2018 | 53-1 v EvertonWest Ham United 3-1 Everton | Premier League |
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