| 1 | Sun 13 Sep 2020 | 62-0 v ADO Den HaagHeracles Almelo 2-0 ADO Den Haag | Dutch Eredivisie |
| 2 | Sun 20 Sep 2020 | 60-4 v Willem IIWillem II 4-0 Heracles Almelo | Dutch Eredivisie |
| 3 | Sun 27 Sep 2020 | 6 1-1 v PSV EindhovenHeracles Almelo 1-1 PSV Eindhoven | Dutch Eredivisie |
| 4 | Sat 3 Oct 2020 | 60-3 v VitesseVitesse 3-0 Heracles Almelo | Dutch Eredivisie |
| 5 | Sat 17 Oct 2020 | 60-1 v RKC WaalwijkHeracles Almelo 0-1 RKC Waalwijk | Dutch Eredivisie |
| 6 | Sun 25 Oct 2020 | 6 1-1 v Sparta RotterdamSparta Rotterdam 1-1 Heracles Almelo | Dutch Eredivisie |
| 7 | Sun 22 Nov 2020 | 60-5 v AjaxAjax 5-0 Heracles Almelo | Dutch Eredivisie |
| 8 | Sun 29 Nov 2020 | 61-2 v AZ AlkmaarHeracles Almelo 1-2 AZ Alkmaar | Dutch Eredivisie |
| 9 | Sun 6 Dec 2020 | 60-0 v FeyenoordFeyenoord 0-0 Heracles Almelo | Dutch Eredivisie |
| 10 | Fri 11 Dec 2020 | 61-2 v Fortuna SittardHeracles Almelo 1-2 Fortuna Sittard | Dutch Eredivisie |
| 11 | Sun 20 Dec 2020 | 62-1 v sc Heerenveensc Heerenveen 1-2 Heracles Almelo | Dutch Eredivisie |
| 12 | Wed 23 Dec 2020 | 61-0 v FC GroningenFC Groningen 0-1 Heracles Almelo | Dutch Eredivisie |
| 13 | Sat 9 Jan 2021 | 6 0-2 v VitesseHeracles Almelo 0-2 Vitesse | Dutch Eredivisie |
| 14 | Tue 12 Jan 2021 | 64-0 v FC EmmenHeracles Almelo 4-0 FC Emmen | Dutch Eredivisie |
| 15 | Sat 16 Jan 2021 | 60-2 v FC UtrechtFC Utrecht 2-0 Heracles Almelo | Dutch Eredivisie |
| 16 | Sat 23 Jan 2021 | 61-0 v sc HeerenveenHeracles Almelo 1-0 sc Heerenveen | Dutch Eredivisie |
| 17 | Sat 30 Jan 2021 | 61-0 v FC GroningenHeracles Almelo 1-0 FC Groningen | Dutch Eredivisie |
| 18 | Fri 5 Feb 2021 | 61-0 v Fortuna SittardFortuna Sittard 0-1 Heracles Almelo | Dutch Eredivisie |
| 19 | Sun 21 Feb 2021 | 60-3 v RKC WaalwijkRKC Waalwijk 3-0 Heracles Almelo | Dutch Eredivisie |
| 20 | Sat 27 Feb 2021 | 62-2 v FC TwenteHeracles Almelo 2-2 FC Twente | Dutch Eredivisie |
| 21 | Sat 13 Mar 2021 | 62-1 v ADO Den HaagADO Den Haag 1-2 Heracles Almelo | Dutch Eredivisie |
| 22 | Sun 21 Mar 2021 | 61-1 v Sparta RotterdamHeracles Almelo 1-1 Sparta Rotterdam | Dutch Eredivisie |
| 23 | Sun 4 Apr 2021 | 60-3 v PSV EindhovenPSV Eindhoven 3-0 Heracles Almelo | Dutch Eredivisie |
| 24 | Sat 10 Apr 2021 | 64-0 v Willem IIHeracles Almelo 4-0 Willem II | Dutch Eredivisie |
| 25 | Sun 25 Apr 2021 | 61-3 v FC EmmenFC Emmen 3-1 Heracles Almelo | Dutch Eredivisie |
| 26 | Thu 13 May 2021 | 61-1 v FeyenoordHeracles Almelo 1-1 Feyenoord | Dutch Eredivisie |
| 27 | Sun 16 May 2021 | 60-5 v AZ AlkmaarAZ Alkmaar 5-0 Heracles Almelo | Dutch Eredivisie |
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