| 1 | Tue 27 Oct 2020 | 112-0 v Wigan AthleticMilton Keynes Dons 2-0 Wigan Athletic | Sky Bet League One |
| 2 | Sat 31 Oct 2020 | 111-1 v AFC WimbledonMilton Keynes Dons 1-1 AFC Wimbledon | Sky Bet League One |
| 3 | Tue 3 Nov 2020 | 110-0 v Northampton TownNorthampton Town 0-0 Milton Keynes Dons | Sky Bet League One |
| 4 | Sat 14 Nov 2020 | 112-1 v SunderlandSunderland 1-2 Milton Keynes Dons | Sky Bet League One |
| 5 | Sat 21 Nov 2020 | 111-3 v Hull CityMilton Keynes Dons 1-3 Hull City | Sky Bet League One |
| 6 | Tue 24 Nov 2020 | 112-2 v Shrewsbury TownMilton Keynes Dons 2-2 Shrewsbury Town | Sky Bet League One |
| 7 | Wed 2 Dec 2020 | 111-0 v Charlton AthleticCharlton Athletic 0-1 Milton Keynes Dons | Sky Bet League One |
| 8 | Sat 5 Dec 2020 | 111-2 v Accrington StanleyAccrington Stanley 2-1 Milton Keynes Dons | Sky Bet League One |
| 9 | Tue 15 Dec 2020 | 111-1 v Peterborough UnitedMilton Keynes Dons 1-1 Peterborough United | Sky Bet League One |
| 10 | Sat 19 Dec 2020 | 110-1 v Plymouth ArgylePlymouth Argyle 1-0 Milton Keynes Dons | Sky Bet League One |
| 11 | Sat 9 Jan 2021 | 111-1 v BurnleyBurnley 1-1 Milton Keynes Dons | Emirates FA Cup Third Round |
| 12 | Tue 12 Jan 2021 | 112-0 v Northampton TownNorthampton Town 0-2 Milton Keynes Dons | Papa John’s Trophy Third Round |
| 13 | Sat 23 Jan 2021 | 311-1 v AFC WimbledonCrewe Alexandra 1-1 AFC Wimbledon | Sky Bet League One |
| 14 | Tue 26 Jan 2021 | 311-4 v GillinghamGillingham 4-1 Crewe Alexandra | Sky Bet League One |
| 15 | Sat 30 Jan 2021 | 311-1 v Ipswich TownCrewe Alexandra 1-1 Ipswich Town | Sky Bet League One |
| 16 | Tue 2 Feb 2021 | 311-0 v Shrewsbury TownShrewsbury Town 0-1 Crewe Alexandra | Sky Bet League One |
| 17 | Sat 6 Feb 2021 | 310-2 v Peterborough UnitedPeterborough United 2-0 Crewe Alexandra | Sky Bet League One |
| 18 | Tue 2 Mar 2021 | 311-1 v BlackpoolBlackpool 1-1 Crewe Alexandra | Sky Bet League One |
| 19 | Sat 6 Mar 2021 | 310-3 v Lincoln CityLincoln City 3-0 Crewe Alexandra | Sky Bet League One |
| 20 | Sat 13 Mar 2021 | 310-3 v Burton AlbionCrewe Alexandra 0-3 Burton Albion | Sky Bet League One |
| 21 | Fri 2 Apr 2021 | 311-2 v Hull CityCrewe Alexandra 1-2 Hull City | Sky Bet League One |
| 22 | Mon 5 Apr 2021 | 312-0 v Milton Keynes DonsMilton Keynes Dons 0-2 Crewe Alexandra | Sky Bet League One |
| 23 | Sat 10 Apr 2021 | 310-6 v Oxford UnitedCrewe Alexandra 0-6 Oxford United | Sky Bet League One |
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