| 1 | Sat 5 Sep 2020 | 11-1 v AFC WimbledonOxford United 1-1 AFC Wimbledon | Carabao Cup First Round South |
| 2 | Sat 19 Sep 2020 | 10-2 v SunderlandOxford United 0-2 Sunderland | Sky Bet League One |
| 3 | Sat 26 Sep 2020 | 14-1 v Accrington StanleyAccrington Stanley 1-4 Oxford United | Sky Bet League One |
| 4 | Sat 10 Oct 2020 | 11-3 v GillinghamGillingham 3-1 Oxford United | Sky Bet League One |
| 5 | Sat 17 Oct 2020 | 10-2 v Peterborough UnitedPeterborough United 2-0 Oxford United | Sky Bet League One |
| 6 | Tue 20 Oct 2020 | 13-2 v Milton Keynes DonsOxford United 3-2 Milton Keynes Dons | Sky Bet League One |
| 7 | Tue 27 Oct 2020 | 10-2 v Charlton AthleticCharlton Athletic 2-0 Oxford United | Sky Bet League One |
| 8 | Sat 31 Oct 2020 | 10-2 v Fleetwood TownFleetwood Town 2-0 Oxford United | Sky Bet League One |
| 9 | Tue 3 Nov 2020 | 13-1 v RochdaleOxford United 3-1 Rochdale | Sky Bet League One |
| 10 | Tue 17 Nov 2020 | 10-2 v Crewe AlexandraOxford United 0-2 Crewe Alexandra | Sky Bet League One |
| 11 | Sat 21 Nov 2020 | 12-1 v Wigan AthleticWigan Athletic 1-2 Oxford United | Sky Bet League One |
| 12 | Tue 24 Nov 2020 | 11-1 v PortsmouthPortsmouth 1-1 Oxford United | Sky Bet League One |
| 13 | Sat 28 Nov 2020 | 1 1-2 v Swindon TownOxford United 1-2 Swindon Town | Sky Bet League One |
| 14 | Tue 8 Dec 2020 | 11-1 v Forest Green RoversOxford United 1-1 Forest Green Rovers | Papa John’s Trophy Second Round |
| 15 | Tue 12 Jan 2021 | 11-0 v Cambridge UnitedOxford United 1-0 Cambridge United | Papa John’s Trophy Third Round |
| 16 | Tue 2 Feb 2021 | 13-1 v AFC WimbledonOxford United 3-1 AFC Wimbledon | Papa John’s Trophy Northern Group D |
| 17 | Tue 16 Feb 2021 | 10-2 v Tranmere RoversOxford United 0-2 Tranmere Rovers | Papa John’s Trophy Northern Group E |
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