| 1 | Sun 20 Sep 2020 | 252-0 v Real ValladolidReal Betis 2-0 Real Valladolid | Spanish La Liga |
| 2 | Sun 18 Oct 2020 | 250-3 v Real SociedadReal Betis 0-3 Real Sociedad | Spanish La Liga |
| 3 | Sat 24 Oct 2020 | 250-2 v Atlético MadridAtlético Madrid 2-0 Real Betis | Spanish La Liga |
| 4 | Sun 1 Nov 2020 | 253-1 v ElcheReal Betis 3-1 Elche | Spanish La Liga |
| 5 | Sat 7 Nov 2020 | 252-5 v BarcelonaBarcelona 5-2 Real Betis | Spanish La Liga |
| 6 | Mon 23 Nov 2020 | 250-4 v Athletic BilbaoAthletic Bilbao 4-0 Real Betis | Spanish La Liga |
| 7 | Sat 2 Jan 2021 | 251-1 v SevillaReal Betis 1-1 Sevilla | Spanish La Liga |
| 8 | Mon 11 Jan 2021 | 252-0 v HuescaHuesca 0-2 Real Betis | Spanish La Liga |
| 9 | Fri 19 Mar 2021 | 252-0 v LevanteReal Betis 2-0 Levante | Spanish La Liga |
| 10 | Sun 4 Apr 2021 | 251-1 v ElcheElche 1-1 Real Betis | Spanish La Liga |
| 11 | Sun 11 Apr 2021 | 251-1 v Atlético MadridReal Betis 1-1 Atlético Madrid | Spanish La Liga |
| 12 | Sun 18 Apr 2021 | 252-2 v ValenciaReal Betis 2-2 Valencia | Spanish La Liga |
| 13 | Wed 21 Apr 2021 | 25 0-0 v Athletic BilbaoReal Betis 0-0 Athletic Bilbao | Spanish La Liga |
| 14 | Sat 24 Apr 2021 | 25 0-0 v Real MadridReal Madrid 0-0 Real Betis | Spanish La Liga |
| 15 | Sun 2 May 2021 | 251-1 v Real ValladolidReal Valladolid 1-1 Real Betis | Spanish La Liga |
| 16 | Mon 10 May 2021 | 252-1 v GranadaReal Betis 2-1 Granada | Spanish La Liga |
| 17 | Thu 13 May 2021 | 251-1 v EibarEibar 1-1 Real Betis | Spanish La Liga |
| 18 | Sun 16 May 2021 | 251-0 v HuescaReal Betis 1-0 Huesca | Spanish La Liga |
| 19 | Sat 22 May 2021 | 25 3-2 v Celta VigoCelta Vigo 2-3 Real Betis | Spanish La Liga |
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